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Women are more likely to develop hypothyroidism than men. In population-based studies, women were seven times more likely than men to have TSH levels above 10 mU/L. [8] 2–4% of people with subclinical hypothyroidism will progress to overt hypothyroidism each year. The risk is higher in those with antibodies against thyroid peroxidase.
It makes thyroid stimulating hormone (TSH), which triggers the thyroid to make thyroid hormone. [1] In thyroid disease the immune system makes antibodies that damage thyroid cells and interfere with their ability to make thyroid hormone. Over time, thyroid damage can cause thyroid hormone levels to be too low.
If low thyroid levels are confirmed, hypothyroidism is treated by taking a medication to replace the missing hormone, commonly known as thyroid hormone replacement, says Dr. Waring.
In the US white people are affected more often than black. It is more common in low to middle income groups. Women are more susceptible with a 17.5% rate of prevalence compared to 6% in men. [8] It is the most common cause of hypothyroidism in developed countries. [9] It typically begins between the ages of 30 and 50.
Reader's DigestSilent Signs of a Thyroid ProblemKnow the symptoms of an overactive and underactive thyroid before it interferes with your life. Several mysterious symptoms—from weight changes to ...
TSH levels are determined by a classic negative feedback system in which high levels of T3 and T4 suppress the production of TSH, and low levels of T3 and T4 increase the production of TSH. TSH levels are thus often used by doctors as a screening test, where the first approach is to determine whether TSH is elevated, suppressed, or normal. [25]
Low levels of thyroid hormones can lead to symptoms including fatigue, weight gain, cold intolerance, dry, flakey skin, loss of hair and inability to concentrate.
A low amount of thyroxine (one of the two thyroid hormones) in the blood, due to lack of dietary iodine to make it, gives rise to high levels of thyroid stimulating hormone (TSH), which stimulates the thyroid gland to increase many biochemical processes; the cellular growth and proliferation can result in the characteristic swelling or hyperplasia of the thyroid gland, or goiter.