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The rate of cancer recurrence is determined by many factors, including age, sex, cancer type, treatment duration, stage of advancement, grade of original tumor, and cancer-specific risk factors. [2] [3] [4] If recurrent cancer has already moved to other body parts or has developed chemo-resistance then it may be more aggressive than original ...
Relapse is a term to describe returning symptoms of the disease after a period of remission. In cancer-treatment, doctors usually avoid the term "cured" and instead prefer the term " no evidence of disease " ( NED ) to refer to a complete remission of cancer, which does not rule out the possibility of relapse.
The spontaneous regression and remission from cancer was defined by Everson and Cole in their 1966 book as "the partial or complete disappearance of a malignant tumour in the absence of all treatment, or in the presence of therapy which is considered inadequate to exert significant influence on neoplastic disease." [1]
Thus, relapse is applied only for those plasmodial species that have hypnozoites in the life cycle, such as Plasmodium vivax and P. ovale. On the other hand, recrudescence means that circulating, multiplying parasites are detected after having persisted in the bloodstream (or elsewhere) at undetectable levels for a period of time, as merozoites ...
An upcoming therapy that also leverages T-cell immune response is the class of drugs termed bispecific T-cell engagers (BITE), or sometimes simply bispecific antibodies. The first drug in this class approved for multiple myeloma is Teclistamab, but again its use is presently reserved for patients in later stages of the disease. [99]
Published in 1962, it is hailed as a masterpiece of Urdu literature. [2] [3] It won Mastoor the 1963 Adamjee Literary Award for Urdu prose and has been translated into 13 languages. [4] English translations of the novel by Neelam Hussain titled The Inner Courtyard and by Daisy Rockwell as The Women's Courtyard were published in 2001 and 2018 ...
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CLL has also been reported to convert into other more aggressive diseases such as lymphoblastic lymphoma, hairy cell leukemia, high grade T cell lymphomas, [24] acute myeloid leukemia, [25] lung cancer, brain cancer, melanoma of the eye or skin, [26] [27] salivary gland tumors, and Kaposi's sarcomas. [28]