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Chloroquine retinopathy is a form of toxic retinopathy (damage of the retina) caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. This eye toxicity limits long-term use of the drugs. [3]
A World Health Organization infographic that states that hydroxychloroquine does not prevent illness or death from COVID-19. Chloroquine and hydroxychloroquine are anti-malarial medications also used against some auto-immune diseases. [64] Chloroquine, along with hydroxychloroquine, was an early experimental treatment for COVID-19. [65]
Talk about the controversial medication is floating around again.
Hydroxychloroquine (Plaquenil) is another option and is generally considered safer than methotrexate. However, these prescribed drugs have a range of side effects such as nausea , loss of appetite , dizziness , hair loss , stomach aches/cramps , headache , liver toxicity and increased risk of infections .
Hydroxychloroquine increases [40] lysosomal pH in antigen-presenting cells [19] by two mechanisms: As a weak base, it is a proton acceptor and via this chemical interaction, its accumulation in lysozymes raises the intralysosomal pH, but this mechanism does not fully account for the effect of hydroxychloroquine on pH.
Examples include chloroquine and hydroxychloroquine which are quinine-like. Apart from antimalarial effects, these drugs are also used in the treatment of other diseases such as dermatological , immunological, rheumatological , and severe infectious diseases.
Central serous chorioretinopathy (CSC or CSCR), also known as central serous retinopathy (CSR), is an eye disease that causes visual impairment, often temporary, usually in one eye. [ 1 ] [ 2 ] When the disorder is active it is characterized by leakage of fluid under the retina that has a propensity to accumulate under the central macula.
However, endothelial polymegethism does not seem to return to normal levels even long after the cessation of contact lens wear. [2] Even after a six-month period in which contact lenses are not worn, polymegethism seems to remain. [3] Stromal thickness does not return to a normal level even after an entire month in which contact lens wear is ...