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One of the major symptoms of Shapiro syndrome is the hypothermia. Clonidine , an alpha 2-adrenoreceptor agonist, is a medication commonly used for hypertension. However, clonidine has been found to aid in hypothalamic regulation and is the most effective medication for symptom management in Shapiro syndrome . [ 5 ]
Hypothermia can happen in most mammals in cold weather and can be fatal. Baby mammals such as kittens are unable to regulate their body temperatures and have a risk of hypothermia if they are not kept warm by their mothers. Many animals other than humans often induce hypothermia during hibernation or torpor. [citation needed]
An early stage of hyperthermia can be "heat exhaustion" (or "heat prostration" or "heat stress"), whose symptoms can include heavy sweating, rapid breathing and a fast, weak pulse. If the condition progresses to heat stroke, then hot, dry skin is typical [ 2 ] as blood vessels dilate in an attempt to increase heat loss.
Affected skin becomes numb, which can cause a clumsy walking pattern if the feet are affected; Skin transitions from red to a pale color depending on temperature of exposure [4] [15] After cold exposure. Symptoms can last from a few hours to a few days; During rewarming, skin appears pale blue and continue to be cold, numb, and swollen [4] [15]
Gastrointestinal symptoms such as nausea and vomiting have also been occasionally reported. [ 13 ] Cases of severe overdose have been reported and symptoms displayed might include prolonged deep coma or deep cyclic coma, apnea , respiratory depression, hypoxemia , hypothermia , hypotension , bradycardia , cardiac arrest , and pulmonary ...
Heat illness is a spectrum of disorders due to increased body temperature. It can be caused by either environmental conditions or by exertion.It includes minor conditions such as heat cramps, heat syncope, and heat exhaustion as well as the more severe condition known as heat stroke. [1]
The most serious symptoms of altitude sickness arise from edema (fluid accumulation in the tissues of the body). At very high altitude, humans can get either high-altitude pulmonary edema (HAPE), or high-altitude cerebral edema (HACE). The physiological cause of altitude-induced edema is not conclusively established.
Non-freezing cold injuries (NFCI) is a class of tissue damage caused by sustained exposure to low temperature without actual freezing. [1] There are several forms of NFCI, and the common names may refer to the circumstances in which they commonly occur or were first described, such as trench foot, which was named after its association with trench warfare.