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  2. Nicotine - Wikipedia

    en.wikipedia.org/wiki/Nicotine

    Urinary metabolites of nicotine, quantified as average percentage of total urinary nicotine [146] As nicotine enters the body, it is distributed quickly through the bloodstream and crosses the blood–brain barrier reaching the brain within 10–20 seconds after inhalation. [147] The elimination half-life of nicotine in the body is around two ...

  3. Nicotinic acetylcholine receptor - Wikipedia

    en.wikipedia.org/wiki/Nicotinic_acetylcholine...

    The activation of receptors by nicotine modifies the state of neurons through two main mechanisms. On one hand, the movement of cations causes a depolarization of the plasma membrane (which results in an excitatory postsynaptic potential in neurons ) leading to the activation of voltage-gated ion channels .

  4. CYP2A6 - Wikipedia

    en.wikipedia.org/wiki/CYP2A6

    Cytochrome P450 2A6 (abbreviated CYP2A6) is a member of the cytochrome P450 mixed-function oxidase system, which is involved in the metabolism of xenobiotics in the body. CYP2A6 is the primary enzyme responsible for the oxidation of nicotine and cotinine. It is also involved in the metabolism of several pharmaceuticals, carcinogens, and a ...

  5. Effects of nicotine on human brain development - Wikipedia

    en.wikipedia.org/wiki/Effects_of_nicotine_on...

    How does the nicotine in e-cigarettes affect the brain? [6] Until about age 25, the brain is still growing. [6] Each time a new memory is created or a new skill is learned, stronger connections – or synapses – are built between brain cells. [6] Young people's brains build synapses faster than adult brains. [6]

  6. Nicotinic acid - Wikipedia

    en.wikipedia.org/wiki/Nicotinic_acid

    The American Heart Association strongly advises against the substitution of dietary supplement nicotinic acid for prescription nicotinic acid because of potentially serious side effects, which means that nicotinic acid should only be used under the supervision of a health care professional, and because manufacture of dietary supplement ...

  7. File:Side effects of nicotine.svg - Wikipedia

    en.wikipedia.org/wiki/File:Side_effects_of...

    By this method, body diagrams can be derived by pasting organs into one of the "plain" body images shown below. This method requires a graphics editor that can handle transparent images, in order to avoid white squares around the organs when pasting onto the body image. Pictures of organs are found on the project's main page. These were ...

  8. Nicotinamide adenine dinucleotide - Wikipedia

    en.wikipedia.org/wiki/Nicotinamide_adenine_di...

    The main role of NAD + in metabolism is the transfer of electrons from one molecule to another. Reactions of this type are catalyzed by a large group of enzymes called oxidoreductases . The correct names for these enzymes contain the names of both their substrates: for example NADH-ubiquinone oxidoreductase catalyzes the oxidation of NADH by ...

  9. Cardiac physiology - Wikipedia

    en.wikipedia.org/wiki/Cardiac_physiology

    Cardiac physiology or heart function is the study of healthy, unimpaired function of the heart: involving blood flow; myocardium structure; the electrical conduction system of the heart; the cardiac cycle and cardiac output and how these interact and depend on one another.