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A study published in The Journal of Infectious Diseases in 2024 investigated the reactivation of inherited chromosomally integrated human herpesvirus 6 (iciHHV-6B) in a liver transplant recipient and its impact on the graft. The research, conducted by Hannolainen et al., used hybrid capture sequencing and various molecular techniques to analyze ...
Human herpesvirus 6B affects humans. Primary infection with this virus is the cause of the common childhood illness exanthema subitum (also known as roseola infantum or sixth disease). Additionally, reactivation is common in transplant recipients, which can cause several clinical manifestations such as encephalitis , bone marrow suppression ...
In 1992 the two variants were recognised within Human herpesvirus 6 on the basis of differing restriction endonuclease cleavages, monoclonal antibody reactions, [6] and growth patterns. [7] In 2012 these two variants were officially recognised as distinct species by the International Committee on Taxonomy of Viruses. [8]
Human herpesvirus 7 (HHV-7) Human cytomegalovirus (HCMV, HHV-5) "seems to have a large impact on immune parameters in later life and may contribute to increased morbidity and eventual mortality." [5] Human herpesvirus 6A (HHV-6A) has been described as more neurovirulent, [6] and as such is more frequently found in patients with ...
The herpesvirus was first isolated from the blue wildebeest in 1960 by veterinary scientist Walter Plowright. [4] The genus Herpesvirus was established in 1971 in the first report of the International Committee on Taxonomy of Viruses (ICTV). This genus consisted of 23 viruses and 4 groups of viruses.
They are abundant in the genomes of jawed vertebrates, and they comprise up to 5–8% of the human genome (lower estimates of ~1%). [ 1 ] [ 2 ] An ERV is a vertically inherited proviral sequence and a subclass of a type of gene called a transposon , which can normally be packaged and moved within the genome to serve a vital role in gene ...
HHV Infected Cell Polypeptide 0 (ICP0) gene is expressed very early during lytic infection, and for this reason is called an immediate-early Herpes gene. In 1991, Farrell and colleagues reported that the 2.0-kb LAT intron terminates at the 5′ end with a 750-base antisense RNA complement for the ICP0 gene.
Herpes virus may refer to: Any member of the large family of DNA viruses known as Herpesviridae. Human herpesviruses, nine types of herpesviruses that can cause diseases in humans Herpes simplex virus 1 and 2, responsible for herpes simplex infections; Human alphaherpesvirus 3, also called varicella-zoster virus, responsible for chickenpox and ...