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Human herpesvirus 6 (HHV-6) is the common collective name for human herpesvirus 6A (HHV-6A) and human herpesvirus 6B (HHV-6B). These closely related viruses are two of the nine known herpesviruses that have humans as their primary host. [1]
Human herpesvirus 6B affects humans. Primary infection with this virus is the cause of the common childhood illness exanthema subitum (also known as roseola infantum or sixth disease). Additionally, reactivation is common in transplant recipients, which can cause several clinical manifestations such as encephalitis , bone marrow suppression ...
In 1992 the two variants were recognised within Human herpesvirus 6 on the basis of differing restriction endonuclease cleavages, monoclonal antibody reactions, [6] and growth patterns. [7] In 2012 these two variants were officially recognised as distinct species by the International Committee on Taxonomy of Viruses. [8]
Schematic drawing of a Herpesviridae virion. All members of the Herpesviridae share a common structure; a relatively large, monopartite, double-stranded, linear DNA genome encoding 100–200 genes encased within an icosahedral protein cage (with T=16 symmetry) called the capsid, which is itself wrapped in a protein layer called the tegument containing both viral proteins and viral mRNAs and a ...
The herpesvirus was first isolated from the blue wildebeest in 1960 by veterinary scientist Walter Plowright. [4] The genus Herpesvirus was established in 1971 in the first report of the International Committee on Taxonomy of Viruses (ICTV). This genus consisted of 23 viruses and 4 groups of viruses.
Human herpesvirus 7 (HHV-7) Human cytomegalovirus (HCMV, HHV-5) "seems to have a large impact on immune parameters in later life and may contribute to increased morbidity and eventual mortality." [5] Human herpesvirus 6A (HHV-6A) has been described as more neurovirulent, [6] and as such is more frequently found in patients with ...
Herpes virus may refer to: Any member of the large family of DNA viruses known as Herpesviridae. Human herpesviruses, nine types of herpesviruses that can cause diseases in humans Herpes simplex virus 1 and 2, responsible for herpes simplex infections; Human alphaherpesvirus 3, also called varicella-zoster virus, responsible for chickenpox and ...
The risk of spread between a couple is about 7.5% over a year (for unprotected sex). [6] The likelihood of transferring genital herpes from one person to another is decreased by external condom use by 50%, by internal condom by 50%, and refraining from sex during an active outbreak. [ 6 ]