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“Limbic” is related to the brain areas first involved, “age-related” and the name “LATE” itself refer to the onset of disease usually in persons aged 80 or older. “ TDP-43 ” indicates the aberrant mis-folded protein (or proteinopathy ) deposits in the brain that characterize LATE, and “ encephalopathy ” means illness of brain.
Gerstmann syndrome is typically associated with damage to the inferior parietal lobule of the dominant hemisphere. It is classically considered a left-hemisphere disorder, although right-hemisphere damage has also been associated with components of the syndrome. [2] It is named after Jewish Austrian-born American neurologist Josef Gerstmann. [3]
Deficits in orientation are one of the most common symptoms of brain disease, hence tests of orientation are included in almost all medical and neuropsychological evaluations. [48] While research has primarily focused on levels of orientation among clinical populations, a small number of studies have examined whether there is a normal decline ...
In some cases, older adults seem to be using different strategies than younger adults. For example, brain imaging studies have revealed that older adults are more likely to use both hemispheres when completing memory tasks than younger adults. [51] In addition, older adults sometimes show a positivity effect when remembering information, which ...
The patient had a lesion in the left occipital lobe, blocking sight in the right visual field , and in the splenium of the corpus callosum. Dejerine interpreted this case as a disconnection of the speech area in the left hemisphere from the right visual cortex.
Constructional apraxia cannot be localized to a specific hemisphere or cerebral area because drawing and constructional tasks require both perceptual and motor functioning. [7] [9] It has been linked to parietal lesions in the left and right hemisphere, stroke and Alzheimer's disease.
Of those who have residual symptoms after PRES, this is attributable largely to hemorrhage. [1] [4] Non-resolution of MRI abnormalities has been linked with poorer outcomes. [4] The presence of brain hemorrhage and cytotoxic edema (brain edema with concomittant brain tissue damage) is also associated with a poor prognosis. [2]
Apraxia is most often due to a lesion located in the dominant (usually left) hemisphere of the brain, typically in the frontal and parietal lobes. Lesions may be due to stroke, acquired brain injuries, or neurodegenerative diseases such as Alzheimer's disease or other dementias, Parkinson's disease, or Huntington's disease. Also, apraxia ...