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For most people, the first symptoms result from atheroma progression within the heart arteries, most commonly resulting in a heart attack and ensuing debility. The heart arteries are difficult to track because they are small (from about 5 mm down to microscopic), they are hidden deep within the chest and they never stop moving.
Plaque build-up often doesn’t cause symptoms, but it can block blood flow to vital organs like your heart. Coronary artery disease occurs when atherosclerosis affects the arteries supplying ...
Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), [13] is a type of heart disease involving the reduction of blood flow to the cardiac muscle due to a build-up of atheromatous plaque in the arteries of the heart. [5] [6] [14] It is the most common of the cardiovascular diseases. [15]
In coronary heart disease, the coronary arteries narrow due to the buildup of atheroma or fatty deposits on the vessel walls. The atheroma causes the blood flow of the arteries to be restricted. [6] By restricting the blood flow, the tissue is still receiving some oxygen, but not enough to sustain the tissue over time. [5]
Coronary Artery Disease. Coronary artery disease, or coronary heart disease, is the most common type of heart disease. It occurs when fatty deposits called plaques build up in your arteries ...
A myocardial infarction (MI), or heart attack, arises from complete occlusion of a coronary artery. [9] The most frequent cause of MI is the rupturing of an atherosclerotic plaque formed in CAD. Plaque rupture exposes the subendothelial matrix beneath the plaque, initiating thrombus formation within the vasculature. [7]
The animation shows plaque buildup or a coronary artery spasm can lead to a heart attack and how blocked blood flow in a coronary artery can lead to a heart attack. The most common cause of a myocardial infarction is the rupture of an atherosclerotic plaque on an artery supplying heart muscle.
Stroke is caused by marked narrowing or closure of arteries going to the brain; lack of adequate blood supply leads to the death of the cells of the affected tissue. [26] Peripheral arteries, which supply blood to the legs, arms, and pelvis, also experience marked narrowing due to plaque rupture and clots. Symptoms of the narrowing are pain and ...