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In November 2017, the FDA approved Abilify Mycite, a digital pill containing a sensor intended to record when its consumer takes their medication. [145] [146] A long-acting injectable version of aripiprazole was approved by the FDA for the treatment of bipolar disorder 1 and schizophrenia in April 2023. [8] [147] [148]
Antipsychotics by class Generic name Brand names Chemical class ATC code Typical antipsychotics; Acepromazine: Atravet, Acezine: phenothiazine: N05AA04
Abilify (aripiprazole) – atypical antipsychotic used to treat schizophrenia, bipolar disorder, and irritability associated with autism; Adderall (mixed amphetamine salts) – a stimulant used to treat ADHD; Ambien – nonbenzodiazepine used as a sleep aid; Anafranil (clomipramine) – a tricyclic antidepressant; mostly used to treat OCD
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Aripiprazole lauroxil, sold under the brand name Aristada among others, is a long-acting injectable atypical antipsychotic that was developed by Alkermes. [5] [6] [7] It is an N-acyloxymethyl prodrug of aripiprazole that is administered via intramuscular injection once every four to eight weeks for the treatment of schizophrenia.
Brexpiprazole was developed by Otsuka and Lundbeck, and is considered to be a successor to aripiprazole (Abilify). [15] It was approved for medical use in the United States in July 2015. [ 16 ] [ 17 ] A generic version was approved in August 2022. [ 18 ]
Rank Brand Name(s) Generic Name Sales Q1 2014 Sales ($000) Change from Q4 2013 Company(ies) Disease/Medical Use First Approval Date Patent Expiration Date [6] [7]; 1: Abilify
At least five atypical antipsychotics (lumateperone, [48] cariprazine, [49] lurasidone, [50] olanzapine, [51] and quetiapine [52]) have also been found to possess efficacy in the treatment of bipolar depression as a monotherapy, whereas only olanzapine [53] and quetiapine [54] [55] have been proven to be effective broad-spectrum (i.e., against ...
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