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A synchondrosis (or primary cartilaginous joint) is a type of cartilaginous joint where hyaline cartilage completely joins together two bones. [1] Synchondroses are different from symphyses (secondary cartilaginous joints), which are formed of fibrocartilage , and from synostosis (ossified junctions), which is the fusion of two or more bones.
The Children's Oncology Group (COG), a clinical trials group supported by the National Cancer Institute (NCI), is the world's largest organization devoted exclusively to pediatric cancer research. [1] The COG conducts a spectrum of clinical research and translational research trials for infants, children, adolescents, and young adults with cancer.
Under this model, cancer arises as the result of a single, isolated event, rather than the slow accumulation of multiple mutations. [4] The exact function of some tumor suppressor genes is not currently known (e.g. MEN1, WT1), [5] but based on these genes following the Knudson "two-hit" hypothesis, they are strongly presumed to be suppressor genes.
Rhabdomyosarcoma is the most common soft-tissue sarcoma in children as well as the third most common solid tumor in children. Recent estimates place the incidence of the disease at approximately 4.5 case per 1 million children/adolescents with approximately 250 new cases in the United States each year.
My Child Matters Pediatric Oncology Nurse Award: a campaign to give recognition to the important role that nurses play in the fight against childhood cancer. All qualified nurses can apply by designing a project to help fight against childhood cancer and improve the care of children with cancer, particularly in the most disadvantaged areas of ...
Pediatric brain cancer is the second-leading cause of childhood cancer death, just after leukemia. Recent trends suggest that the rate of overall CNS tumor diagnosis is increasing by about 2.7% per year. As diagnostic techniques using genetic markers improve and are used more often, the proportion of AT/RT diagnoses is expected to increase.
In 2013, the Zach Sobiech Osteosarcoma Fund was established to designate funding specifically for osteosarcoma research. It's administered by the Children's Cancer Research Fund and donations fund research at the University of Minnesota. The fund honors Zach Sobiech, a musician who died of osteosarcoma in May 2013 at age 18.
Children whose cranial plates fuse too early may suffer deformities and brain damage as the skull does not expand properly to accommodate the growing brain, a condition known as craniosynostosis. Synchondrosis is a cartilaginous joint connected by hyaline cartilage , as seen in the epiphyseal plate .