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13653 Ensembl ENSG00000120738 ENSMUSG00000038418 UniProt P18146 P08046 RefSeq (mRNA) NM_001964 NM_007913 RefSeq (protein) NP_001955 NP_031939 Location (UCSC) Chr 5: 138.47 – 138.47 Mb Chr 18: 34.99 – 35 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse EGR-1 (Early growth response protein 1) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by ...
Cis-regulatory DNA sequences that are located in DNA regions distant from the promoters of genes can have very large effects on gene expression, with some genes undergoing up to 100-fold increased expression due to such a cis-regulatory sequence. [3] These cis-regulatory sequences include enhancers, silencers, insulators and tethering elements. [4]
GM fish have been developed with promoters driving an over-production of "all fish" growth hormone for use in the aquaculture industry, to increase the speed of development and potentially reduce fishing pressure on wild stocks. This has resulted in dramatic growth enhancement in several species, including salmon, [111] trout, [112] and tilapia ...
Methods to study promoter activity commonly are based in the expression of a reporter gene from the promoter of the gene of interest. [16] [2] [17] Mutations and deletions are made in a promoter region, and their changes on couple expression of the reporter gene are measured. [18] The most important reporter genes are the fluorescence proteins ...
Allosteric regulation of an enzyme. In the fields of biochemistry and pharmacology an allosteric regulator (or allosteric modulator) is a substance that binds to a site on an enzyme or receptor distinct from the active site, resulting in a conformational change that alters the protein's activity, either enhancing or inhibiting its function.
Energy drink company Celsius struggled last year as its growth rate nosedived. Investors were quick to dump the stock after learning that a key partner and distributor, PepsiCo , was reducing its ...
In 2023, it delivered 1.81 million EVs, beating Wall Street's expectations and marking a 38% increase from 2022. In Q1 of 2024, however, Tesla’s vehicle deliveries fell 8.5% year over year to ...
A transcriptional activator is a protein (transcription factor) that increases transcription of a gene or set of genes. [1] Activators are considered to have positive control over gene expression, as they function to promote gene transcription and, in some cases, are required for the transcription of genes to occur.