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Polyisobutene (polyisobutylene) is a class of organic polymers prepared by polymerization of isobutene. The polymers often have the formula Me 3 C[CH 2 CMe 2] n H (Me = CH 3). They are typically colorless gummy solids. Cationic polymerization, initiated with a strong Brønsted or Lewis acid, is the typical method for its production.
Pirfenidone 1800 or 1200 mg/day reduced the mean decline in vital capacity from baseline to week 52 compared with placebo. Progression-free survival was also improved with pirfenidone compared with placebo. [46] Two randomized, double-blind, placebo-controlled Phase III studies in eleven countries across Europe, North America, and Australia. [47]
Amisulpride is approved and used at low doses in the treatment of dysthymia and major depressive disorder. [10] [20] [11] [21] [22] [23] Whereas typical doses used in schizophrenia block postsynaptic dopamine D 2-like receptors and reduce dopaminergic neurotransmission, low doses of amisulpride preferentially block presynaptic dopamine D 2 and D 3 autoreceptors and thereby disinhibit dopamine ...
The 1972 edition of the Physicians' Desk Reference lists Obetrol containing (10 mg tablet): 2.5 mg methamphetamine saccharate; 2.5 mg methamphetamine hydrochloride; 2.5 mg racemic amphetamine sulfate; 2.5 mg dextroamphetamine sulfate; Obetrol was also available in 20 mg tablets which contained twice the quantity of its ingredients, in the same ...
Felbamate is available in tablets (400 mg and 600 mg) and as a peach-coloured oral suspension (600 mg/5 mL). Adults (≥ 14 years): begin with 1,200 mg daily given every 6 to 8 hours Children (2–14 years): 15 to 45 mg per kg per day given every 6 to 8 hours
Erdosteine, administered in single doses from 150 mg to 1200 mg to adult volunteers, shows a linear kinetic, with Met I serum concentration approximately 4-fold higher than those of erdosteine. The pharmacokinetic parameters of erdosteine and Met I are fully comparable after single and multiple doses, therefore there is no accumulation or ...
Mesterolone is used in androgen replacement therapy at a dosage of 50 to 100 mg 2 to 3 times per day. [16. ... 150–1,200 mg/3–6 months Notes: ...
MST Continus is a 12-hour release formula, therefore it is given 2 times per day. It is available in the following doses: 5 mg, 10 mg, 15 mg, 30 mg, 60 mg, 100 mg and 200 mg tablets (equating to between 0.416 mg/hour and 16.67 mg/hour).