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Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders characterized by impaired cortisol synthesis. [1] [2] It results from the deficiency of one of the five enzymes required for the synthesis of cortisol in the adrenal cortex. [3]
Adrenal gland disorders (or diseases) are conditions that interfere with the normal functioning of the adrenal glands. [1] Your body produces too much or too little of one or more hormones when you have an adrenal gland dysfunction. The type of issue you have and the degree to which it affects your body's hormone levels determine the symptoms.
Regarding nonclassic CAH, glucocorticoid therapy is typically not necessary for lifelong management. However, in certain cases, this treatment may be required to address fertility issues such as oligomenorrhea, amenorrhea, or difficulty conceiving. About 90% of women with nonclassic CAH remain undiagnosed.
Late onset congenital adrenal hyperplasia (LOCAH), also known as nonclassic congenital adrenal hyperplasia (NCCAH or NCAH), is a milder form of congenital adrenal hyperplasia (CAH), [1] a group of autosomal recessive disorders characterized by impaired cortisol synthesis that leads to variable degrees of postnatal androgen excess.
An adrenocortical adenoma or adrenal adenoma is commonly described as a benign neoplasm emerging from the cells that comprise the adrenal cortex.Like most adenomas, the adrenocortical adenoma is considered a benign tumor since the majority of them are non-functioning and asymptomatic.
Metastasis to one or both adrenal glands is the most common form of malignant adrenal lesion, and the second most common adrenal tumor after benign adenomas. [4] Primary tumors in such cases are most commonly from lung cancer (39%), breast cancer (35%), malignant melanoma , gastrointestinal tract cancer , pancreas cancer , and renal cancer .
Pages in category "Adrenal gland disorders" The following 34 pages are in this category, out of 34 total. This list may not reflect recent changes. ...
[1] [10] A single adrenal gland may also be removed in cases where only one is enlarged. [4] In cases due to enlargement of both glands, treatment is typically with medications known as aldosterone antagonists such as spironolactone or eplerenone. [1] Other medications for high blood pressure and a low salt diet, e.g. DASH diet, may also be needed.