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Glipizide, sold under the brand name Glucotrol among others, is an anti-diabetic medication of the sulfonylurea class used to treat type 2 diabetes. [1] [2] It is used together with a diabetic diet and exercise. [1] [2] It is not indicated for use by itself in type 1 diabetes. [1] [2] It is taken by mouth.
Drugs used in diabetes treat types of diabetes mellitus by decreasing glucose levels in the blood. With the exception of insulin , most GLP-1 receptor agonists ( liraglutide , exenatide , and others), and pramlintide , all diabetes medications are administered orally and are thus called oral hypoglycemic agents or oral antihyperglycemic agents.
Glimepiride is an antidiabetic medication within the sulfonylurea class, primarily prescribed for the management of type 2 diabetes. [1] [2] It is regarded as a second-line option compared to metformin, due to metformin's well-established safety and efficacy. [1]
For this study, researchers analyzed medical data from almost 394,000 adults 40 years and older with type 2 diabetes and active COPD that were taking GLP-1, SGLT-2, or DPP-4i medications.
As a result, different GLP-1 agonist drugs are modified in various ways to extend the half-life, resulting in drugs that can be dosed multiple times per day, daily, weekly, or less often. [29] Most synthetic GLP-1 agonists are delivered via subcutaneous injection , which is a barrier to their use and reason for discontinuation. [ 37 ]
The study analyzed records of more than 125,000 adults who began taking the GLP-1 drugs liraglutide, semaglutide, or tirzepatide between January 2018 and December 2023. These drugs are prescribed ...
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Interactions are important for SGLT2 inhibitors because most people with type 2 diabetes are taking many other medications. Gliflozins appear to increase the diuretic effect of thiazides , loop diuretics and related diuretics and may increase the risk of dehydration and hypotension . [ 23 ]
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