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  2. What is gabapentin? Here's why it's so controversial. - AOL

    www.aol.com/gabapentin-heres-why-controversial...

    While gabapentin can be helpful in a number of circumstances, some of the common side effects associated with taking the drug as directed include drowsiness, dizziness, headache, dry mouth, weight ...

  3. Gabapentin - Wikipedia

    en.wikipedia.org/wiki/Gabapentin

    Sleepiness and dizziness are the most common side effects. Serious side effects include respiratory depression, and allergic reactions. [7] As with all other antiepileptic drugs approved by the FDA, gabapentin is labeled for an increased risk of suicide. Lower doses are recommended in those with kidney disease. [7] Gabapentin was first approved ...

  4. Opioid - Wikipedia

    en.wikipedia.org/wiki/Opioid

    This requires them to increase their drug dosage to maintain the benefit, and that in turn also increases the unwanted side effects. [78] Long-term opioid use can cause opioid-induced hyperalgesia, which is a condition in which the patient has increased sensitivity to pain. [101] All of the opioids can cause side effects. [70]

  5. Drug withdrawal - Wikipedia

    en.wikipedia.org/wiki/Drug_withdrawal

    Drug withdrawal, drug withdrawal syndrome, or substance withdrawal syndrome [1] is the group of symptoms that occur upon the abrupt discontinuation or decrease in the intake of pharmaceutical or recreational drugs. In order for the symptoms of withdrawal to occur, one must have first developed a form of drug dependence.

  6. Opioid withdrawal - Wikipedia

    en.wikipedia.org/wiki/Opioid_withdrawal

    A major feature of opioid withdrawal is exacerbated noradrenaline release in the locus coeruleus. Alpha-2 adrenergic receptor agonists can be used to manage the symptoms of acute withdrawal. Lofexidine and clonidine are used for this purpose; both are considered to be equally effective, though clonidine has more side effects than lofexidine. [16]

  7. Opioid agonist therapy - Wikipedia

    en.wikipedia.org/wiki/Opioid_agonist_therapy

    Conversely, an opioid agonist induces minimal effects and stays in the brain for a long time, which prevents the opioid user from feeling the effects of natural or synthetic opioids. [3] However, the opioid receptors are still being used when an opioid agonist attaches, which prevents the effects of opioid withdrawal and can help prevent ...

  8. Lofexidine - Wikipedia

    en.wikipedia.org/wiki/Lofexidine

    When these two drugs are paired, naltrexone is administered to induce an opioid receptor blockade, sending the subject into immediate withdrawal and accelerating the detoxification process, while lofexidine is given to relieve the symptoms associated with the withdrawal including chills, sweating, stomach cramps, muscle pain, and runny nose.

  9. Can Gabapentin Really Cause ED? - AOL

    www.aol.com/lifestyle/gabapentin-really-cause-ed...

    Gabapentin is also associated with other intimate side effects, like difficulty reaching orgasm, although the science on this link isn’t totally clear. ED from gabapentin isn’t permanent.

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