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The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. It does not include any risks conferred by pharmaceutical agents or their metabolites in breast milk. Every drug has specific information listed in its product literature.
Women should speak to their doctor or healthcare professional before starting or stopping any medications while pregnant. [1] Drugs taken in pregnancy including over-the counter-medications, prescription medications, nutritional supplements, recreational drugs, and illicit drugs may cause harm to the mother or the unborn child.
Megestrol acetate is the lead drug of this class for the management of cachexia, and medroxyprogesterone acetate is also used. [ 43 ] [ 44 ] The mechanism of action of the appetite-related effects of these two medications is unknown and may not be related to their progestogenic activity.
In addition to drug-specific contraindications, [41] several general factors may contraindicate delaying childbirth with the use of tocolytic medications. Fetus is older than 34 weeks gestation [49] Fetus weighs less than 2.5 kg, or has intrauterine growth restriction (IUGR) [49] or placental insufficiency [49]
A drug class is a group of medications and other compounds that share similar chemical structures, act through the same mechanism of action (i.e., binding to the same biological target), have similar modes of action, and/or are used to treat similar diseases. [1] [2] The FDA has long worked to classify and license new medications.
A uterotonic, also known as an oxytocic or ecbolic, is a type of medication used to induce contraction or greater tonicity of the uterus. Uterotonics are used both to induce labor and to reduce postpartum hemorrhage. [1] Labor induction in the third trimester of pregnancy may be
[33] [22] [34] A large number of synthetic progestogens, or progestins, have been derived from progesterone and are used as medications as well. [20] Examples include medroxyprogesterone acetate and norethisterone. [20] In 2022, it was the 125th most commonly prescribed medication in the United States, with more than 5 million prescriptions ...
Package inserts for prescription drugs often include a separate document called a "patient package insert" with information written in plain language intended for the end-user—the person who will take the drug or give the drug to another person, such as a minor. Inserts for over-the-counter medications are also written plainly. [1] [2]