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Catabolite Activator Protein (blue) bound to a piece of DNA (red). In cell biology, catabolite activator protein (CAP), which is also known as cAMP receptor protein (CRP), is a trans-acting transcriptional activator in bacteria that effectively catalyzes the initiation of DNA transcription by interacting with RNA polymerase in a way that causes the DNA to bend.
Sequence coverage (or depth) is the number of unique reads that include a given nucleotide in the reconstructed sequence. [1] [2] Deep sequencing refers to the general concept of aiming for high number of unique reads of each region of a sequence. [3] Physical coverage, the cumulative length of reads or read pairs expressed as a multiple of ...
[1] [2] CRP then activates transcription through direct protein–protein interactions with RNA polymerase. [1] [2] The genes regulated by CRP are mostly involved in energy metabolism, such as galactose, citrate, or the PEP group translocation system. [3] [4] In Escherichia coli, CRP can regulate the transcription of more than 100 genes. [5]
An entity which provides insurance is known as an insurer, insurance company, insurance carrier, or underwriter. A person or entity who buys insurance is known as a policyholder, while a person or entity covered under the policy is called an insured. The insurance transaction involves the policyholder assuming a guaranteed, known, and ...
Biology is the scientific study of life. [ 1 ] [ 2 ] [ 3 ] It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. [ 1 ] [ 2 ] [ 3 ] For instance, all organisms are composed of at least one cell that processes hereditary information encoded in genes , which can be transmitted ...
In insurance, the insurance policy is a contract (generally a standard form contract) between the insurer and the policyholder, which determines the claims which the insurer is legally required to pay. In exchange for an initial payment, known as the premium, the insurer promises to pay for loss caused by perils covered under the policy language.
[8] Prescription drug plans are a form of insurance offered through some health insurance plans. In the U.S., the patient usually pays a copayment and the prescription drug insurance part or all of the balance for drugs covered in the formulary of the plan. [5]: TS 2:21 Such plans are routinely part of national health insurance programs. For ...
After the first round of translation ("pioneer round"), CBC20/80 is replaced by the translation initiation factor eIF4E. [2] The eIF4F complex (eIF4E, eIF4G and eIF4A ) then regulates translation in response to the state of the cell via its phosphorylation state and again protects the message from decapping.