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  2. Hereditary nonpolyposis colorectal cancer - Wikipedia

    en.wikipedia.org/wiki/Hereditary_nonpolyposis...

    Hereditary nonpolyposis colorectal cancer (HNPCC) is a hereditary predisposition to colon cancer.. HNPCC includes (and was once synonymous with) [1] Lynch syndrome, an autosomal dominant genetic condition that is associated with a high risk of colon cancer, endometrial cancer (second most common), ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. [2]

  3. The Key to Reducing Your Colon Cancer Risk by 17% May Already ...

    www.aol.com/key-reducing-colon-cancer-risk...

    Specifically, they found a 17% lower risk of colorectal cancer for every 300 milligrams of calcium consumed per day. This means that if you drink about a cup of milk per day—which contains ...

  4. Colorectal cancer - Wikipedia

    en.wikipedia.org/wiki/Colorectal_cancer

    The signs and symptoms of colorectal cancer depend on the location of the tumor in the bowel, and whether it has spread elsewhere in the body ().The classic warning signs include: worsening constipation, blood in the stool, decrease in stool caliber (thickness), loss of appetite, loss of weight, and nausea or vomiting in someone over 50 years old. [15]

  5. Familial adenomatous polyposis - Wikipedia

    en.wikipedia.org/wiki/Familial_adenomatous_polyposis

    The incidence of the mutation is between 1 in 10,000 and 1 in 15,000 births. By age 35 years, 95% of individuals with FAP (>100 adenomas) have polyps. Without colectomy, colon cancer is virtually inevitable. The mean age of colon cancer in untreated individuals is 39 years (range 34–43 years). [13]

  6. Checkpoint inhibitor induced colitis - Wikipedia

    en.wikipedia.org/wiki/Checkpoint_inhibitor...

    Cancer immunotherapy treatment: Risk factors: Caucasian, NSAID use, anti-CTLA4 treatment, melanoma, history of prior checkpoint inhibitor induced colitis, Faecalibacterium in fecal microbiota: Diagnostic method: Colonoscopy, stool tests for infection: Differential diagnosis: Infectious colitis, gastrointestinal metastases (rare) Prevention ...

  7. Colorectal polyp - Wikipedia

    en.wikipedia.org/wiki/Colorectal_polyp

    Hereditary nonpolyposis colorectal cancer (HNPCC, also known as Lynch syndrome) is a hereditary colorectal cancer syndrome. [9] It is the most common hereditary form of colorectal cancer in the United States and accounts for about 3% of all cases of cancer. [9] It was first recognized by Alder S. Warthin in 1885 at the University of Michigan. [9]

  8. Ulcerative colitis - Wikipedia

    en.wikipedia.org/wiki/Ulcerative_colitis

    The risk of colorectal cancer is significantly increased in people with ulcerative colitis after ten years if involvement is beyond the splenic flexure. People with backwash ileitis might have an increased risk for colorectal carcinoma. [171] Those people with only proctitis usually have no increased risk. [19]

  9. Mismatch repair cancer syndrome - Wikipedia

    en.wikipedia.org/wiki/Mismatch_repair_cancer...

    Under the name constitutional mismatch repair-deficiency (CMMR-D), it has been mapped to MLH1, MSH2, MSH6 or PMS2. [2] Monoallelic mutations of these genes are observed in the condition known as Lynch syndrome or hereditary nonpolyposis colorectal cancer, while biallelic mutations are observed in CMMR-D. [3] People expressing the HNPCC (which itself is considered autosomal dominant) trait are ...

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