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Azithromycin stands apart from other macrolide antibiotics because it is a weak inhibitor of CYP3A4, and does not significantly increase AUC value of co-administered drugs. [ 49 ] The difference in CYP3A4 inhibition by macrolides has clinical implications, for example for people who take statins , which are cholesterol -lowering drugs that are ...
Generally, antibiotics (like azithromycin [150]) are not effective against viruses, only some bacteria. [152] Azithromycin is sometimes given to patients hospitalized with COVID-19, but only to treat bacterial co-infection. Overuse of azithromycin causes antibiotic resistance, and rare side effects include heart arrhythmias and hearing loss ...
Another example is Azithromycin-resistant Neisseria gonorrhoeae, which developed a resistance to azithromycin in 2011. [154] In gram-negative bacteria, plasmid-mediated resistance genes produce proteins that can bind to DNA gyrase, protecting it from the action of quinolones.
The evolution of bacteria on a "Mega-Plate" petri dish A list of antibiotic resistant bacteria is provided below. These bacteria have shown antibiotic resistance (or antimicrobial resistance). Gram positive Clostridioides difficile Clostridioides difficile is a nosocomial pathogen that causes diarrheal disease worldwide. Diarrhea caused by C. difficile can be life-threatening. Infections are ...
Although this procedure has not been officially approved by the US FDA, its use is permitted under some conditions in patients with antibiotic-resistant C. difficile infection. Cure rates are around 90%, and work is underway to develop stool banks, standardized products, and methods of oral delivery. [173]
One of President Donald Trump's big goals for his second term is to reduce the number of federal workers. To do this, the administration has offered so-called "buyout" packages that about 75,000 ...
The production of a β-lactamase by a bacterium does not necessarily rule out all treatment options with β-lactam antibiotics. In some instances, β-lactam antibiotics may be co-administered with a β-lactamase inhibitor. For example, Augmentin (FGP) is made of amoxicillin (a β-lactam antibiotic) and clavulanic acid (a β-lactamase inhibitor).
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