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Methylene blue has been described as "the first fully synthetic drug used in medicine." Methylene blue was first prepared in 1876 by German chemist Heinrich Caro. [69] Its use in the treatment of malaria was pioneered by Paul Guttmann and Paul Ehrlich in 1891. During this period before the first World War, researchers like Ehrlich believed that ...
Notably, methylene blue is used as as the main treatment for methemoglobinemia, however in G6PD individuals, methylene blue may cause further oxidative stress and that may induce or worsen hemolysis in those with methemoglobinemia [1]. Hemolytic anemia may also occur secondarily due to thrombotic microangiopathy after exposure to certain drugs.
Treatment is generally with oxygen therapy and methylene blue. [3] Other treatments may include vitamin C, exchange transfusion, and hyperbaric oxygen therapy. [3] Outcomes are generally good with treatment. [3] Methemoglobinemia is relatively uncommon, with most cases being acquired rather than genetic. [3]
Wright's stain is a hematologic stain that facilitates the differentiation of blood cell types. It is classically a mixture of eosin (red) and methylene blue dyes. It is used primarily to stain peripheral blood smears, urine samples, and bone marrow aspirates, which are examined under a light microscope.
Methylene blue If you have a history of heart problems — such as QT prolongation and heart rhythm disturbance — you should talk to your healthcare provider before taking escitalopram.
The methylene blue allows the methaemoglobin to be converted to haemoglobin. Supportive treatment is also usually provided, depending on the severity of the toxicity, that resulted in the anaemia. [11] Ascorbic acid is used to treat methemoglobinemia, a symptom of naphthalene poisoning and is used when methylene blue is not available, or in ...
The carbon footprint of blue inhalers is being compared to a lengthy car trip in advice released to asthma patients as British doctors are told to switch out the sprays for a more effective treatment.
Chromoendoscopy is a medical procedure wherein dyes (often the same stains used in histology) are instilled into the gastrointestinal tract at the time of visualization with fibre-optic endoscopy. The purpose of chromoendoscopy is chiefly to enhance the characterization of tissues , although dyes may be used for other functional purposes.
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