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Likelihood Ratio: An example "test" is that the physical exam finding of bulging flanks has a positive likelihood ratio of 2.0 for ascites. Estimated change in probability: Based on table above, a likelihood ratio of 2.0 corresponds to an approximately +15% increase in probability.
Diagram relating pre- and post-test probabilities, with the green curve (upper left half) representing a positive test, and the red curve (lower right half) representing a negative test, for the case of 90% sensitivity and 90% specificity, corresponding to a likelihood ratio positive of 9, and a likelihood ratio negative of 0.111.
The negative predictive value is defined as: = + = where a "true negative" is the event that the test makes a negative prediction, and the subject has a negative result under the gold standard, and a "false negative" is the event that the test makes a negative prediction, and the subject has a positive result under the gold standard.
Thus the likelihood-ratio test tests whether this ratio is significantly different from one, or equivalently whether its natural logarithm is significantly different from zero. The likelihood-ratio test, also known as Wilks test , [ 2 ] is the oldest of the three classical approaches to hypothesis testing, together with the Lagrange multiplier ...
The likelihood ratio is central to likelihoodist statistics: the law of likelihood states that degree to which data (considered as evidence) supports one parameter value versus another is measured by the likelihood ratio. In frequentist inference, the likelihood ratio is the basis for a test statistic, the so-called likelihood-ratio test.
In medical testing with binary classification, the diagnostic odds ratio (DOR) is a measure of the effectiveness of a diagnostic test. [1] It is defined as the ratio of the odds of the test being positive if the subject has a disease relative to the odds of the test being positive if the subject does not have the disease.
The commonly used chi-squared tests for goodness of fit to a distribution and for independence in contingency tables are in fact approximations of the log-likelihood ratio on which the G-tests are based. [4] The general formula for Pearson's chi-squared test statistic is
For larger samples, asymptotic approximations are accurate enough and easier to calculate. One of these approximations is the likelihood ratio. An alternative hypothesis can be defined under which each value is replaced by its maximum likelihood estimate = .