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A Jarisch–Herxheimer reaction is a sudden and typically transient reaction that may occur within 24 hours of being administered antibiotics for an infection by a spirochete, including syphilis, leptospirosis, Lyme disease, and relapsing fever. [1]
Symptoms of the condition in women may consist of menstrual irregularities, amenorrhea, abnormal vaginal bleeding, and enlargement of the uterus and breasts. [ 1 ] [ 2 ] It may also present as isosexual precocity in children [ 1 ] [ 2 ] and as hypogonadism , gynecomastia , feminization , impotence , and loss of libido in males. [ 3 ]
Treatments for hot flashes vary, depending on their severity, frequency and cause. "When women have milder symptoms, we suggest avoiding things that can trigger hot flashes, including hot or spicy ...
Jarisch–Herxheimer reaction in a person with syphilis and human immunodeficiency virus [71] One of the potential side effects of treatment is the Jarisch–Herxheimer reaction. [3] It frequently starts within one hour and lasts for 24 hours, with symptoms of fever, muscle pains, headache, and a fast heart rate. [3]
Why doctors hesitate to prescribe hormone therapy. One of the barriers to women getting treatment for menopause symptoms is the reluctance some doctors have to prescribe hormone replacement ...
Metformin itself isn’t thought to cause hair loss, but type 2 diabetes and PCOS (polycystic ovary syndrome) — the conditions it’s prescribed to treat — can cause hair loss.
Research on hot flashes is mostly focused on treatment options. The exact cause and pathogenesis, or causes, of vasomotor symptoms (VMS)—the clinical name for hot flashes—has not yet been fully studied. [11] [12] Hot flashes are associated with declining levels of estrogen (estrogen withdrawal) and other hormonal changes. [13]
All patients treated with antibiotics should be observed during the first 4 hours of treatment for a Jarisch-Herxheimer reaction, which is a worsening of symptoms characterized by rigors, hypotension, and high fever. [5] The reaction occurs in over 50% of cases and may be difficult to distinguish from a febrile crisis. [5]