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Liver disease, or hepatic disease, is any of many diseases of the liver. [1] If long-lasting it is termed chronic liver disease. [3] Although the diseases differ in ...
Indian childhood cirrhosis is a chronic liver disease of childhood characterised by cirrhosis of the liver [1] associated with the deposition of copper in the liver. [2] [3] [4] It primarily affects children of 1–3 years of age and has a genetic predisposition.
Other causes include: infiltrative liver diseases, granulomatous liver disease, abscess, amyloidosis of the liver and peripheral arterial disease. Mild elevation of ALP can be seen in liver cirrhosis, hepatitis, and congestive cardiac failure. Transient hyperphosphataemia is a benign condition in infants, and can reach normal level in 4 months.
Liver transplantation is the standard of care in people presenting with fulminant liver failure or those with the progression of disease despite multiple lines of therapy. [ 33 ] [ 34 ] [ 35 ] Many patients, once started on long-term immunosuppressive therapy, will remain on that treatment for life.
Chronic liver disease takes several years to develop and the condition may not be recognised unless there is clinical awareness of subtle signs and investigation of abnormal liver function tests. Testing for chronic liver disease involves blood tests, imaging including ultrasound, and a biopsy of the liver. The liver biopsy is a simple ...
Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, chronic liver failure or chronic hepatic failure and end-stage liver disease, is a condition of the liver in which the normal functioning tissue, or parenchyma, is replaced with scar tissue and regenerative nodules as a result of chronic liver disease.
Symptoms and laboratory findings suggestive of liver disease should prompt further tests and can thus help establish a diagnosis of hepatitis C infection early on. [ 16 ] Following the acute phase, the infection may resolve spontaneously in 10–50% of affected people; this occurs more frequently in young people and females.
A complete blood test can help distinguish intrinsic liver disease from extrahepatic bile-duct obstruction. [19] An ultrasound of the liver can reliably detect a dilated biliary-duct system, [20] it can also detect the characteristics of a cirrhotic liver. [21] Computerized tomography (CT) can give accurate anatomical information for a complete ...
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