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The hippocampus (pl.: hippocampi; via Latin from Greek ἱππόκαμπος, 'seahorse'), also hippocampus proper, is a major component of the brain of humans and many other vertebrates. In the human brain the hippocampus, the dentate gyrus, and the subiculum are components of the hippocampal formation located in the limbic system.
In humans and other primates, the portion of the hippocampus near the base of the temporal lobe is much broader than the part at the top. Due to the three-dimensional curvature of the hippocampus, two-dimensional sections are commonly presented. Neuroimaging can show a number of different shapes, depending on the angle and location of the cut.
Hippocampal sclerosis (HS) or mesial temporal sclerosis (MTS) is a neuropathological condition with severe neuronal cell loss and gliosis in the hippocampus. [1] Neuroimaging tests such as magnetic resonance imaging (MRI) and positron emission tomography (PET) may identify individuals with hippocampal sclerosis. [2]
The dentate gyrus (DG) is one of the subfields of the hippocampus, in the hippocampal formation. The hippocampal formation is located in the temporal lobe of the brain, and includes the hippocampus (including CA1 to CA4) subfields, and other subfields including the dentate gyrus, subiculum, and presubiculum. [1] [2]
The uncus is an anterior extremity of the parahippocampal gyrus.It is separated from the apex of the temporal lobe by a sulcus called the rhinal sulcus. [1] Although superficially continuous with the hippocampal gyrus, the uncus forms morphologically a part of the rhinencephalon.
The hippocampal subfields are four subfields CA1, CA2, CA3, and CA4 that make up the structure of the hippocampus. Regions described in the hippocampus are the head, body, and tail, and other hippocampal subfields include the dentate gyrus , the presubiculum , and the subiculum .
The hippocampal formation is a compound structure in the medial temporal lobe of the brain. It forms a c-shaped bulge on the floor of the inferior horn of the lateral ventricle . [ 1 ] Typically, the hippocampal formation is said to included the dentate gyrus , the hippocampus , and the subiculum . [ 2 ]
The calcar avis, (calcarine spur) previously known as the hippocampus minor, [1] is an involution of the wall of the lateral ventricle's posterior horn produced by the calcarine fissure. [ 2 ] It is sometimes visible on ultrasound [ 3 ] and can resemble a clot .