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Type 3 diabetes is a proposed pathological linkage between Alzheimer's disease and certain features of type 1 and type 2 diabetes. [1] Specifically, the term refers to a set of common biochemical and metabolic features seen in the brain in Alzheimer's disease, and in other tissues in diabetes; [1] [2] it may thus be considered a "brain-specific type of diabetes."
Dementia, however, can present early in its disease course with depressive symptoms, meaning that this association could actually be reflecting that dementia causes late life depression. [23] Studies that have directly tried to determine whether depression is an independent risk factor for dementia have led to inconclusive results.
Diagnosis of mixed dementia can be difficult, as often only one type will predominate. This makes the treatment of people with mixed dementia uncommon, with many people missing out on potentially helpful treatments. Mixed dementia can mean that symptoms onset earlier, and worsen more quickly since more parts of the brain will be affected. [15]
Some drugs used to treat type 2 diabetes could also help lower a person’s risk of neurodegenerative diseases, such as Alzheimer’s. Image credit: martin-dm/Getty Images.
Dementia is a devastating condition that impacts almost 10% of older adults in the U.S. With that, it’s understandable to want to do what you can to lower the risk of developing it in the future.
Older adults with diabetes are at a higher risk of developing Alzheimer’s disease and other forms of dementia. New research suggests that blood sugar stability, measured by HbA1c time in range ...
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