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Peptic ulcers are present in around 4% of the population. [1] New ulcers were found in around 87.4 million people worldwide during 2015. [5] About 10% of people develop a peptic ulcer at some point in their life. [9] Peptic ulcers resulted in 267,500 deaths in 2015, down from 327,000 in 1990.
An ulcer is a sore on the skin or a mucous membrane, accompanied by the disintegration of tissue. Ulcers can result in complete loss of the epidermis and often portions of the dermis and even subcutaneous fat. Ulcers are most common on the skin of the lower extremities and in the gastrointestinal tract. An ulcer that appears on the skin is ...
Ulcerative colitis (UC) is one of the two types of inflammatory bowel disease (IBD), with the other type being Crohn's disease. [1] It is a long-term condition that results in inflammation and ulcers of the colon and rectum.
Turck feeds dogs Bacillus coli and produces ulcers. [7] 1907 Berkley Moynihan suggests that acid is a cause of ulcers. [1] 1910 Schwartz publishes the excess acid theory of the ulcer, coining the famous phrase "no acid, no ulcer." [2] Gibelli claims to be unable to reproduce Turck's study where he artificially created ulcers by feeding dogs ...
Solitary rectal ulcer syndrome (SRUS) is a rare benign disease characterized by symptoms, clinical findings, and histological abnormalities. [9] Only 40% of patients have ulcers; 20% of patients have a single ulcer, and the remaining lesions range in size and form from broad-based polypoid to hyperemic mucosa. [10]
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Gene Clark (1944–1991, aged 46) had perforated ulcer and died on May 24, 1991. Doug Hepburn (1926–2000, aged 74) had a perforated ulcer and died on November 22, 2000. Philip Agee (1935–2008, aged 72) had a perforated ulcer and died on January 7, 2008. Barbara Bush (1925–2018, aged 92) was treated for a perforated ulcer in November 2008. [9]
Classically, there is a solitary ulcer. But only 20% of patients have a single ulcer whereas in other cases there may be multiple lesions. [6] The size of the ulcers is usually 0.5–4 cm. [5] The lesion is most often located on the anterior (front) or lateral (side) rectal wall, centered on a rectal fold, [1] usually 10 cm from the anal verge. [8]
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