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The endothelium (pl.: endothelia) is a single layer of squamous endothelial cells that line the interior surface of blood vessels and lymphatic vessels. [1] The endothelium forms an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.
Using stem cells for cell replacement therapies is known as "regenerative medicine", which is a booming field that is now working on transplanting cells as opposed to bigger tissues or organs. [22] There was another study done that also showed that after exposure to sevoflurane, the EPCs were able to adhere to endothelial cells better. [23]
Circulating endothelial cells (CECs) are endothelial cells that have been shed from the lining of the vascular wall into the blood stream. [1] Endothelial cells normally line blood vessels to maintain vascular integrity and permeability, but when these cells enter into the circulation, this could be a reflection of vascular dysfunction and damage. [2]
Liver sinusoidal endothelial cells (LSECs) form the lining of the smallest blood vessels in the liver, also called the hepatic sinusoids. LSECs are highly specialized endothelial cells with characteristic morphology and function. They constitute an important part of the reticuloendothelial system (RES).
The lymphatic endothelium refers to a specialized subset of endothelial cells located in the sinus systems of draining lymph nodes.Specifically, these endothelial cells line the branched sinus systems formed by afferent lymphatic vessels, forming a single-cell layer which functions in a variety of critical physiological processes.
Endothelial activation is a proinflammatory and procoagulant state of the endothelial cells lining the lumen of blood vessels. [1] It is most characterized by an increase in interactions with white blood cells (leukocytes), and it is associated with the early states of atherosclerosis and sepsis , among others. [ 2 ]
Vascular endothelial stem cells have been defined as rare endothelial colony forming cells with extremely high proliferative potential. [5] They have been identified by marker analysis as lin- (lineage negative) CD31 +, CD105 +, Sca-1 +, CD117 (ckit) + and thought have the ability to generate functional vasculature from single cells.
Cell type % cell count: Erythrocytes (red blood cells) 84.0 Platelets: 4.9 Bone marrow cells 2.5 Vascular endothelial cells: 2.1 Lymphocytes: 1.5 Hepatocytes: 0.8 Neurons and glia: 0.6 Bronchial endothelial cells: 0.5 Epidermal cells: 0.5 Respiratory interstitial cells: 0.5 Adipocytes (fat cells) 0.2 Dermal fibroblasts: 0.1 Muscle cells: 0.001 ...