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The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.
People with Schizophrenia appear to have a high rate of self-medication with nicotine; the therapeutic effect likely occurs through dopamine modulation by nicotinic acetylcholine receptors. However, there was controversy and conflicting findings over whether postmortem findings resulted from drug tolerance to chronic antipsychotic treatment.
Recent studies have used fMRI to explore specific brain networks, such as the salience network and default mode network, to understand their roles in schizophrenia-related symptoms. Alterations in these networks may affect self-referential thoughts and responses to external stimuli, potentially contributing to symptoms like hallucinations and ...
People with schizophrenia are commonly exploited and victimized by violent crime as part of a broader dynamic of social exclusion. [25] [26] People diagnosed with schizophrenia are also subject to forced drug injections, seclusion, and restraint at high rates. [31] [32] The risk of violence by people with schizophrenia is small.
Through MRIs, psychiatrists can see specific structural differences in the brains of people with schizophrenia and bipolar disorder. These differences include volume of gray matter, neuropathological size differences variations and cortical thickness, which are associated with cognitive differences on tests.
People with schizophrenia can have a job or actually speak to people or can do things themselves," said Hammer. Schizophrenia is a brain disease and patients' symptoms run a spectrum ...
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