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Fexofenadine, sold under the brand name Allegra among others, [10] is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever and urticaria. [ 11 ] Therapeutically, fexofenadine is a selective peripheral H 1 blocker .
It contains fexofenadine, as the hydrochloride, an antihistamine; and pseudoephedrine, as the hydrochloride, a nasal decongestant. [ 2 ] In 2021, it was the 279th most commonly prescribed medication in the United States, with more than 800,000 prescriptions.
Tylol Hot (made by NOBEL Ä°LAÇ SANAYÄ°Ä° VE TÄ°CARET A.Åž., Turkey) — a packet of 20 g contains 60 mg pseudoephedrine hydrochloride, 500 mg paracetamol and 4 mg chlorpheniramine maleate; Unifed (made by United Pharmaceutical Manufacturer, Jordan) — contains pseudoephedrine hydrochloride (also triprolidine and guaifenesin).
Today, Triprolidine is used less frequently and has been replaced in popular medications by other antihistamines like Diphenhydramine, Promethazine, Chlorpheniramine, as well as second generation antihistamines like Loratadine and Fexofenadine. Triprolidine remains an ingredient in the cold medicine Actifed in many territories.
Rupatadine is a second generation, non-sedating, long-acting histamine antagonist with selective peripheral H 1 receptor antagonist activity. It further blocks the receptors of the platelet-activating factor (PAF) according to in vitro and in vivo studies.
Acrivastine is a medication used for the treatment of allergies and hay fever.It is a second-generation H1-receptor antagonist antihistamine (like its base molecule triprolidine) and works by blocking histamine H1 receptors.
Quifenadine (Russian: хифенадин, trade name: Phencarol, Фенкарол) is a 2nd generation antihistamine drug, marketed mainly in post-Soviet countries. [2] [3] Chemically, it is a quinuclidine derivative.
The WHO Model List of Essential Medicines (aka Essential Medicines List or EML [1]), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system. [2]
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