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Positive feedback (exacerbating feedback, self-reinforcing feedback) is a process that occurs in a feedback loop which exacerbates the effects of a small disturbance. That is, the effects of a perturbation on a system include an increase in the magnitude of the perturbation. [ 1 ]
Positive feedback loops play a role by switching cells from low to high Cdk-activity. The interaction between the two types of loops is evident in mitosis. While positive feedback initiates mitosis, a negative feedback loop promotes the inactivation of the cyclin-dependent kinases by the anaphase-promoting complex.
Light switch, a bistable mechanism. In a dynamical system, bistability means the system has two stable equilibrium states. [1] A bistable structure can be resting in either of two states. An example of a mechanical device which is bistable is a light switch. The switch lever is designed to rest in the "on" or "off" position, but not between the ...
Positive feedback occurs when the fed-back signal is in phase with the input signal. Under certain gain conditions, positive feedback reinforces the input signal to the point where the output of the device oscillates between its maximum and minimum possible states. Positive feedback may also introduce hysteresis into a circuit. This can cause ...
Combined saddle-node bifurcations in a system can generate multistability. Bistability (a special case of multistability) is an important property in many biological systems, often the result of network architecture containing a mix of positive feedback interactions and ultra-sensitive elements.
In membrane biology, the Hodgkin cycle is a key component of membrane physiology that describes bioelectrical impulses, especially prevalent in neural and muscle tissues. It was identified by British physiologist and biophysicist Sir Alan Lloyd Hodgkin.
Negative feedback processes are those that maintain particular conditions by reducing (hence 'negative') the difference from a desired state, such as where a thermostat turns on a heater when it is too cold and turns a heater off when it is too hot. Positive feedback processes increase (hence 'positive') the difference from a desired state. An ...
Oscillations are an important type of cell signaling characterized by the periodic change of the system in time. [1] Oscillations can take place in a biological system in a multitude of ways. Positive feedback loops, on their own or in combination with negative feedback are a common feature of oscillating biological systems. [2]