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2. Apixaban - Wikipedia

   en.wikipedia.org/wiki/Apixaban

   Apixaban, sold under the brand name Eliquis, is an anticoagulant medication used to treat and prevent blood clots and to prevent stroke in people with nonvalvular ...

3. Discovery and development of direct Xa inhibitors - Wikipedia

   en.wikipedia.org/wiki/Discovery_and_development...

   The p-methoxy group of apixaban connects to S1 pocket of FXa but does not appear to have any interaction with any residues in this region of FXa. The pyrazole N-2 nitrogen atom of apixaban interacts with Gln-192 and the carbonyl oxygen interacts with Gly-216. The phenyl lactam group of apixaban is positioned between Tyr-99 and Phe-174 and due ...

4. Direct factor Xa inhibitors - Wikipedia

   en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

   Direct factor Xa inhibitors include rivaroxaban, apixaban and edoxaban, and are types of direct oral anticoagulant (DOAC), which are blood thinning drugs, one of the classes of antithrombotic drugs.

5. Anticoagulant - Wikipedia

   en.wikipedia.org/wiki/Anticoagulant

   An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. [1] Some occur naturally in blood-eating animals, such as leeches and mosquitoes, which help keep the bite area unclotted long enough for the animal to obtain blood.

6. Medicare targets popular weight loss drugs Ozempic, Wegovy ...

   www.aol.com/medicare-targets-popular-weight-loss...

   Medicare will seek to negotiate lower list prices for the blockbuster diabetes and weight loss drugs Ozempic and Wegovy and 14 other medications, a cost-saving move that would take effect in 2027 ...

7. 2 High-Yield Dividend Stocks to Buy Early in 2025 - AOL

   www.aol.com/2-high-yield-dividend-stocks...

   This strong market position generates substantial cash flows that support shareholder returns. Turning to the specifics, the pharmaceutical giant offers investors a 4.3% dividend yield backed by a ...

8. Thrombin time - Wikipedia

   en.wikipedia.org/wiki/Thrombin_time

   Thrombin time can be prolonged by heparin, fibrin degradation products, and fibrinogen deficiency or abnormality. Thrombin time is not affected by anti-Xa anticoagulants such as rivaroxaban or apixaban, but is very sensitive to direct thrombin inhibitors including dabigatran, argatroban, and bivalirudin. [5]

9. Ozempic’s health benefits keep growing, but are the risks ...

   www.aol.com/ozempic-health-benefits-keep-growing...

   A major new study has revealed a long list of benefits and some little-known risks of Ozempic and other GLP-1 medications. Experts break down the findings.