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  2. National Institutes of Health Stroke Scale - Wikipedia

    en.wikipedia.org/wiki/National_Institutes_of...

    The National Institutes of Health Stroke Scale, or NIH Stroke Scale (NIHSS), is a tool used by healthcare providers to objectively quantify the impairment caused by a stroke and aid planning post-acute care disposition, though was intended to assess differences in interventions in clinical trials. The NIHSS was designed for the National ...

  3. Tissue-type plasminogen activator - Wikipedia

    en.wikipedia.org/wiki/Tissue-type_plasminogen...

    5327 18791 Ensembl ENSG00000104368 ENSMUSG00000031538 UniProt P00750 P11214 RefSeq (mRNA) NM_033011 NM_000930 NM_000931 NM_001319189 NM_008872 RefSeq (protein) NP_000921 NP_001306118 NP_127509 NP_032898 Location (UCSC) Chr 8: 42.17 – 42.21 Mb Chr 8: 23.25 – 23.27 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Tissue-type plasminogen activator, short name tPA, is a protein that ...

  4. Stroke - Wikipedia

    en.wikipedia.org/wiki/Stroke

    The American Academy of Emergency Medicine had previously stated that objective evidence regarding the applicability of tPA for acute ischemic stroke was insufficient. [175] In 2013 the American College of Emergency Medicine refuted this position, [176] acknowledging the body of evidence for the use of tPA in ischemic stroke; [177] but debate ...

  5. Alteplase - Wikipedia

    en.wikipedia.org/wiki/Alteplase

    Alteplase, sold under the brand name Activase among others, is a biosynthetic form of human tissue-type plasminogen activator (t-PA). It is a thrombolytic medication used to treat acute ischemic stroke, acute ST-elevation myocardial infarction (a type of heart attack), pulmonary embolism associated with low blood pressure, and blocked central venous catheter. [5]

  6. Cerebral infarction - Wikipedia

    en.wikipedia.org/wiki/Cerebral_infarction

    Cerebral infarction, also known as an ischemic stroke, is the pathologic process that results in an area of necrotic tissue in the brain (cerebral infarct). [1] In mid to high income countries, a stroke is the main reason for disability among people and the 2nd cause of death. [2]

  7. New drug's potentially fatal side effects obscured by ... - AOL

    www.aol.com/news/drugs-potentially-fatal-side...

    And when stroke patients are taken to an emergency room, the first treatment doctors often consider is a clot-dissolving medicine called tPA, which ... The company follows guidelines for sharing ...

  8. Cerebroprotectant - Wikipedia

    en.wikipedia.org/wiki/Cerebroprotectant

    A cerebroprotectant (formerly known as a neuroprotectant) is a drug that is intended to protect the brain after the onset of acute ischemic stroke. [1] As stroke is the second largest cause of death worldwide and a leading cause of adult disability, over 150 drugs have been tested in clinical trials to provide cerebroprotection.

  9. CHA2DS2–VASc score - Wikipedia

    en.wikipedia.org/wiki/CHA2DS2–VASc_score

    A high score corresponds to a greater risk of stroke, while a low score corresponds to a lower risk of stroke. The CHADS 2 score is simple and has been validated by many studies. [ 2 ] In clinical use, the CHADS 2 score (pronounced "chads two") has been superseded by the CHA 2 DS 2 -VASc score ("chads vasc" [ 3 ] ), which gives a better ...