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Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. [4] [5] [6] It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares.
[3] [4] Methylprednisolone succinate is provided as two different salts when used as a pharmaceutical drug: a sodium salt (methylprednisolone sodium succinate; brand name Solu-Medrol, others) and a hydrogen salt (methylprednisolone hemisuccinate or methylprednisolone hydrogen succinate; brand name Urbason). [3] [4]
The medicine is used to treat the symptoms of common colds, the flu, and allergies and is not meant to cure the cold or flu. There are many side effects that may occur when using this medicine. These side effects can include nausea, dizziness, and an upset stomach. [4]
The cough started when I was around 25 or 26. I noticed it right before the pandemic, and I didn’t have a bad flu or anything that brought it on. It was consistent, and I had to clear my throat ...
First-generation antihistamines such as chlorpheniramine and clemastine are more potent but have greater sedatory effects; later-generation antihistamines may be used to reduce these effects. [7] Azelastine , a topical antihistamine, is approved for both allergic and non-allergic rhinitis due to its unique anti-inflammatory effects separate ...
Prednisolone can also be used for allergic reactions ranging from seasonal allergies to drug allergic reactions. [25] Prednisolone can also be used as an immunosuppressant for organ transplants. [7] [26] Prednisolone in lower doses can be used in cases of adrenal insufficiency due to Addison's disease. [27] [28]
A small study found honey may be a minimally effective cough treatment due to "well-established antioxidant and antimicrobial effects" and a tendency to soothe irritated tissue. [21] A Cochrane review found there was weak evidence to recommend for or against the use of honey in children as a cough remedy. [22]
[1] [4] [5] Methylprednisolone acetate was previously suspended with polyethylene glycol but is no longer formulated with this excipient due to concerns about possible toxicity. [6] [8] Depo methylprednisolone acetate is a depot injection and is absorbed slowly with a duration of weeks to months with a single intramuscular injection. [5]
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