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A bipolar neuron, or bipolar cell, is a type of neuron characterized by having both an axon and a dendrite extending from the soma (cell body) in opposite directions. These neurons are predominantly found in the retina and olfactory system. [ 1 ]
Bipolar neurons have two main dendrites at opposing ends of the cell body. Many inhibitory neurons have this morphology. Unipolar neurons, typical for insects, have a stalk that extends from the cell body that separates into two branches with one containing the dendrites and the other with the terminal buttons.
Bipolar cells receive synaptic input from either rods or cones, or both rods and cones, though they are generally designated rod bipolar or cone bipolar cells. There are roughly 10 distinct forms of cone bipolar cells, however, only one rod bipolar cell, due to the rod receptor arriving later in the evolutionary history than the cone receptor ...
Bipolar neurons: Sensory neurons that have two processes coming off the soma, one dendrite and one axon; Pseudounipolar neurons: Sensory neurons that have one process that splits into two branches, forming the axon and dendrite; Unipolar brush cells: Are excitatory glutamatergic interneurons that have a single short dendrite terminating in a ...
Midget bipolars are linked to one cone while diffuse bipolars take groups of receptors. Diffuse bipolars can take signals from up to 50 rods or can be a flat cone form and take signals from seven cones. The bipolar cells corresponds to the intermediary cells between the touch and heat receptors on the skin and the medulla or spinal cord. [1]
The cell bodies of unipolar neurons are always found in ganglia. Sensory reception is a peripheral function, so the cell body is in the periphery, though closer to the CNS in a ganglion. The axon projects from the dendrite endings, past the cell body in a ganglion, and into the central nervous system. Bipolar: 1 axon and 1 dendrite.
In neurons, the types of ion channels in the membrane usually vary across different parts of the cell, giving the dendrites, axon, and cell body different electrical properties. As a result, some parts of the membrane of a neuron may be excitable (capable of generating action potentials), whereas others are not.
One illustrative example is the Purkinje cell protein 4 in knockout mice, which exhibit impaired locomotor learning and markedly altered synaptic plasticity in Purkinje neurons. [ 11 ] [ 12 ] PCP4 accelerates both the association and dissociation of calcium (Ca 2+ ) with calmodulin (CaM) in the cytoplasm of Purkinje cells, and its absence ...
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