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Selenium deficiency occurs when an organism lacks the required levels of selenium, a critical nutrient in many species.Deficiency, although relatively rare in healthy well-nourished individuals, [1] can have significant negative results, [2] affecting the health of the heart and the nervous system; contributing to depression, anxiety, and dementia; and interfering with reproduction and gestation.
Selenium deficiency: Significant negative results, [29] affecting the health of the heart, Keshan disease and the nervous system; contributing to depression, anxiety, and dementia; and interfering with reproduction and gestation. People dependent on food grown from selenium-deficient soil may be at risk for deficiency. [30] Sodium deficiency
Selenium deficiency as defined by low (<60% of normal) selenoenzyme activity levels in brain and endocrine tissues only occurs when a low selenium status is linked with an additional stress, such as high exposures to mercury [27] or as a result of increased oxidant stress due to vitamin E deficiency. [28]
The biology of depression is the attempt to identify a biochemical origin of depression, as opposed to theories that emphasize psychological or situational causes. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD) . [ 1 ]
Selenium is found in metal sulfide ores, where it substitutes for sulfur. Commercially, selenium is produced as a byproduct in the refining of these ores. Minerals that are pure selenide or selenate compounds are rare. The chief commercial uses for selenium today are glassmaking and pigments. Selenium is a semiconductor and is used in photocells.
The team used health data from more than 350,000 people who had been recruited for the UK Biobank study between 2006 and 2010 and participated in follow-up assessments three times over the next ...
It may be treated with selenium supplementation, but there is a 30–45% mortality rate. [7] Other sequelae include aspiration pneumonia, failure of passive transfer, and stunting of growth. Clinical laboratory changes include evidence of rhabdomyolysis (elevated CK and AST, myoglobinuria ) and low blood selenium levels.
Micronutrient deficiency is defined as the sustained insufficient supply of vitamins and minerals needed for growth and development, as well as to maintain optimal health. Since some of these compounds are considered essentials (we need to obtain them from the diet), micronutrient deficiencies are often the result of an inadequate intake.