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An increase in serum creatinine can be due to increased ingestion of cooked meat (which contains creatinine converted from creatine by the heat from cooking) or excessive intake of protein and creatine supplements, taken to enhance athletic performance. Intense exercise can increase creatinine by increasing muscle breakdown.
[5] [6] In the late 1920s, after finding that the intramuscular stores of creatine can be increased by ingesting creatine in larger than normal amounts, scientists discovered phosphocreatine (creatine phosphate), and determined that creatine is a key player in the metabolism of skeletal muscle. It is naturally formed in vertebrates. [7]
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In clinical practice, however, creatinine clearance or estimates of creatinine clearance based on the serum creatinine level are used to measure GFR. Creatinine is produced naturally by the body ( creatinine is a breakdown product of creatine phosphate , which is found in muscle).
Creatine is found in foods like red meat, fish, poultry and even dairy products (though at much lower levels), but the average dose in these foods is about one to two grams per pound, says White.
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Creatine-alpha-ketoglutarate is a salt formed from alpha-ketoglutaric acid (AKG) and creatine. Creatine is a mass-produced fitness supplement that is supposed to increase the user's muscle mass, strength and power. Creatine requires a delivery system for cell uptake. [citation needed] An example is arginine alpha-ketoglutarate.
We spoke with certified personal trainers who reveal the six best creatine supplements they highly recommend and have even tried out themselves!"Creatine 6 Best Creatine Supplements, According to ...
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