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A drug combination chart designed for harm reduction by TripSit [1]. Polysubstance use or multisubstance use is the use of combinations of psychoactive substances with both legal and illegal substances.
For example, both Zolpidem and alcohol affect GABA A receptors, and their simultaneous consumption results in the overstimulation of the receptor, which can lead to loss of consciousness. When two drugs affect each other, it is a drug–drug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1]
Combined drug intoxication use often carries with it more risk than use of a single drug, due to an increase in side effects, and drug synergy. The potentiating effect of one drug on another is sometimes considerable and here the licit drugs and medicines – such as alcohol , nicotine and antidepressants – have to be considered in ...
Alcohol, Tobacco, Cannabis, Solvents, 4-MTA, LSD, GHB, Ecstasy, Alkyl nitrites and Khat get zero or very low values in the category 'intravenous harm' (I guess simply because it is not possible at all to use the drug this way or not possible for the drug to have the desired effect this way), but for the average harm over these low values is ...
According to the then-surgeon general's report, a woman who has two drinks a day faces a nearly 22% chance of developing an alcohol-related cancer, compared with a 16.5% risk for a woman drinking ...
Alcohol abuse encompasses a spectrum of alcohol-related substance abuse, ranging from the consumption of more than 2 drinks per day on average for men, or more than 1 drink per day on average for women, to binge drinking or alcohol use disorder. Alcohol advertising Alcohol advertising on college campuses Alcohol and Native Americans
Most of the drugs were rated significantly less harmful than alcohol, with most of the harm befalling the user. The authors explain that one of the limitation of this study is that drug harms are functions of their availability and legal status in the UK, and so other cultures' control systems could yield different rankings.
English: A rational scale to assess the harm of drugs. Data source is the March 24, 2007 article: Nutt, David, Leslie A King, William Saulsbury, Colin Blakemore. "Development of a rational scale to assess the harm of drugs of potential misuse" The Lancet 2007; 369:1047-1053.