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In cell biology and pathophysiology, cellular adaptation refers to changes made by a cell in response to adverse or varying environmental changes. The adaptation may be physiologic (normal) or pathologic (abnormal). Morphological adaptations observed at the cellular level include atrophy, hypertrophy, hyperplasia, and metaplasia. [1]
Evolution of cells refers to the evolutionary origin and subsequent evolutionary development of cells. Cells first emerged at least 3.8 billion years ago [ 1 ] [ 2 ] [ 3 ] approximately 750 million years after Earth was formed.
Experimental evolution of mammalian cells harboring synthetic gene circuits [59] reveals the role of cellular heterogeneity in the evolution of drug resistance, with implications for chemotherapy resistance of cancer cells.
Adaptation is related to biological fitness, which governs the rate of evolution as measured by changes in allele frequencies. Often, two or more species co-adapt and co-evolve as they develop adaptations that interlock with those of the other species, such as with flowering plants and pollinating insects .
According to Kukushkin, the memories stored in non-brain cells in other parts of the body are memories strictly related to the roles that those specific cells play in human health. Thus, he detailed:
Evolutionary physiology is the study of the biological evolution of physiological structures and processes; that is, the manner in which the functional characteristics of organisms have responded to natural selection or sexual selection or changed by random genetic drift across multiple generations during the history of a population or species. [2]
The outcome of evolution is not a perfectly designed organism. The end products of natural selection are organisms that are adapted to their present environments. Natural selection does not involve progress towards an ultimate goal. Evolution does not strive for more advanced, more intelligent, or more sophisticated life forms. [25]
This raises an important issue, which is that many of these tests for adaptive evolution are very weak. Therefore, the fact that many estimates are at (or very near to) 0% does not rule out the occurrence of any adaptive evolution in the human genome, but simply shows that positive selection is not frequent enough to be detected by the tests.
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