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In this situation it is generally uncommon to talk about half-life in the first place, but sometimes people will describe the decay in terms of its "first half-life", "second half-life", etc., where the first half-life is defined as the time required for decay from the initial value to 50%, the second half-life is from 50% to 25%, and so on.
The half-life depends on the age of the animal, as age is related to prolonged duration of anesthesia and recovery time. [18] Toxicity occurs with repeated administration, given that the metabolic clearance of the drug is usually calculated as 7– 9 times the half-life, which is 4 to 5 days for the clearance of xylazine.
The emergence of the muons is caused by the collision of cosmic rays with the upper atmosphere, after which the muons reach Earth. The probability that muons can reach the Earth depends on their half-life, which itself is modified by the relativistic corrections of two quantities: a) the mean lifetime of muons and b) the length between the upper and lower atmosphere (at Earth's surface).
In clinical practice, this means that it takes 4 to 5 times the half-life for a drug's serum concentration to reach steady state after regular dosing is started, stopped, or the dose changed. So, for example, digoxin has a half-life (or t 1 / 2 ) of 24–36 h; this means that a change in the dose will take the best part of a week to ...
(If N(t) is discrete, then this is the median life-time rather than the mean life-time.) This time is called the half-life, and often denoted by the symbol t 1/2. The half-life can be written in terms of the decay constant, or the mean lifetime, as: / = = ().
One of its great advantages is that any sample provides two clocks, one based on uranium-235's decay to lead-207 with a half-life of about 700 million years, and one based on uranium-238's decay to lead-206 with a half-life of about 4.5 billion years, providing a built-in crosscheck that allows accurate determination of the age of the sample ...
Safest Small Cars 2025 Mazda 3. The stylish Mazda 3 has a lot to offer compact-car shoppers, including great looks, a composed driving experience, and reasonable fuel economy from its base 2.0 ...
The plateau principle is a mathematical model or scientific law originally developed to explain the time course of drug action (pharmacokinetics). [1] The principle has wide applicability in pharmacology, physiology, nutrition, biochemistry, and system dynamics.
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