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Marstacimab, sold under the brand name Hympavzi, is a monoclonal antibody medication used for the treatment of hemophilia A and hemophilia B. [1] [4] [2] It is a tissue factor pathway inhibitor (TFPI) antagonist. [4] It was developed by Pfizer. [5]
The most common side effects with Novoseven include venous thromboembolic events (problems caused by blood clots in the veins), rash, pruritus (itching), urticaria (hives), fever and reduced effectiveness of treatment. [4] The most common side effects with Cevenfacta include injection site discomfort and hematoma (a collection of blood under ...
Concizumab, sold under the brand name Alhemo, is a monoclonal antibody used for the treatment of hemophilia A and hemophilia B. [5] [8] It is an anti-tissue factor pathway inhibitor. [5] [8] The most common adverse reactions include injection site reactions and hives (urticaria). [11]
Hympavzi is the first and only anti-tissue factor pathway inhibitor (anti-TFPI) approved in the U.S. for hemophilia A or B and the first hemophilia medicine approved in the U.S. to be administered via
Valoctocogene roxaparvovec, sold under the brand name Roctavian, is a gene therapy used for the treatment of hemophilia A. [ 1 ] [ 3 ] It was developed by BioMarin Pharmaceutical . [ 4 ] [ 5 ] [ 6 ] Valoctocogene roxaparvovec is made of a virus (AAV5) that has been modified to contain the gene for factor VIII, which is lacking in people with ...
In hemophilia A and von Willebrand disease, it should only be used for mild to moderate cases. [1] It may be given in the nose, by injection into a vein, by mouth, or under the tongue. [1] Common side effects include headaches, diarrhea, and low blood sodium. [1] The low blood sodium that results may cause seizures. [1]
Dave Coulier shared an update amid his ongoing treatment for stage 3 non-Hodgkin lymphoma, saying “it’s been a little bit of an adjustment” not having hair. “I realize how much that hair ...
Damoctocog alfa pegol, sold under the brand name Jivi is a recombinant DNA-derived, Factor VIII concentrate used to treat hemophilia A. [5] [6] The most common side effects include headache, cough, nausea, and fever. [5] Damoctocog alfa pegol was approved for medical use in the United States in August 2018, [7] and in the European Union in ...
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