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MCF-7 Cells. MCF-7 is a breast cancer cell line isolated in 1970 from a 69-year-old White woman. [1] MCF-7 is the acronym of Michigan Cancer Foundation-7, referring to the institute in Detroit where the cell line was established in 1973 by Herbert Soule and co-workers. [2]
The E-SCREEN cell proliferation assay is performed with the human MCF-7 breast cancer cell line, an established estrogenic cell line that endogenously expresses ERα. [ 1 ] [ 3 ] [ 4 ] Human MCF-7 are cultivated in Dulbecco’s modified Eagle’s medium (DMEM) with fetal bovine serum (FBS) and phenol red as buffer tracer (culture medium), at 37 ...
Cell line Primary tumor Origin of cells Estrogen receptors Progesterone receptors ERBB2 amplification Mutated TP53 [Notes 2] Tumorigenic in mice Reference External links 600MPE ...
T-47D cells have been employed in studies of the effects of progesterone on breast cancer and the corresponding transcriptional regulation caused by introduced drugs. [3] T-47D cells can be implanted into immunodeficient mice, forming xenografts that can undergo drug testing with corresponding receptor status and angiogenesis changes.
How long: You can typically store bread—homemade, artisanal, or store-bought—for up to 3 months. Thaw it on the counter overnight or reheat it in the oven or toaster straight from frozen ...
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With a capacity of 50 pounds of grain or pellets and 25 pounds of dog/cat food, this feeder is designed with larger pets (think horses) in mind, though the Quick Feeder is versatile, with portions ...
Well, it recently yielded a fat 6.6%! And better still, its shares seem attractively valued, with a recent forward-looking price-to-earnings (P/E) ratio of 8.7, well below the five-year average of ...