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But dosing guidelines from the 1980s until 2008 recommended vancomycin trough concentrations between 5 and 15 μg/mL. [37] Concern for treatment failures prompted recommendations for higher dosing (troughs 15 to 20 μg/mL) for serious infection, and acute kidney injury (AKI) rates attributable to the vancomycin increased.
A drug of last resort (DoLR), also known as a heroic dose, [1] is a pharmaceutical drug which is tried after all other drug options have failed to produce an adequate response in the patient. Drug resistance , such as antimicrobial resistance or antineoplastic resistance , may make the first-line drug ineffective, especially in case of ...
Outpatient parenteral antibiotic therapy (OPAT) is used to administer non-oral antibiotics (usually intravenously) without the need for ongoing hospitalisation.OPAT is particularly useful for people who are not severely ill but do require a prolonged course of treatment that cannot be given in oral form. [1]
May be more narrow-spectrum than vancomycin, resulting in less bowel microbiota alteration. [9] Nausea (11%), vomiting, and abdominal pain. [10] Bactericidal in susceptible organisms such as C. difficile by inhibiting RNA polymerase, thereby inhibiting protein synthesis. [10] Monobactams; Aztreonam: Azactam: Gram-negative bacteria
Oral administration of a liquid. In pharmacology and toxicology, a route of administration is the way by which a drug, fluid, poison, or other substance is taken into the body. [1] Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration ...
Each week during the 2024-25 NBA season, we will take a deeper dive into some of the league’s biggest storylines in an attempt to determine whether trends are based more in fact or fiction ...
It also provides up to 9% of the daily manganese needs for adults, an essential mineral critical for bone health, and about 11% of the daily needs for pantothenic acid (vitamin B5), which plays a ...
The following other wikis use this file: Usage on ar.wikipedia.org فانكوميسين; Usage on azb.wikipedia.org وانکومایسین; Usage on ca.wikipedia.org
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