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Erythema nodosum (EN) is an inflammatory condition characterized by inflammation of subcutaneous fat tissue, resulting in painful red/blue lumps or nodules that are usually seen symmetrically on both shins, on the thighs, arms, and elsewhere. [1] It can be caused by a variety of conditions but 20 to 50% of cases are idiopathic.
In the majority of the time, nodules are not painful or disabling in any way. They are usually more of an unsightly nuisance. However, rheumatoid nodules can become painful when infection or ulcers occur on the skin of the nodule. Some nodules may disappear over time, but other may grow larger, making nodular size difficult to predict. [6]
Chondrodermatitis nodularis chronica helicis (CNCH) is a small, nodular, tender, chronic inflammatory lesion occurring on the helix of the ear, most often in men. [2]: 610 it often presents as a benign painful erythematous nodule fixed to the cartilage of the helix or antihelix of the external ear. [3]
Nodular acne is characterized by large, painful, and persistent pimples. Experts explain what to know about the condition, including causes and treatment.
Angiolipoleiomyomas are acquired, solitary, asymptomatic acral nodules, characterized histologically by well-circumscribed subcutaneous tumors composed of smooth muscle cells, blood vessels, connective tissue, and fat. [7]: 627 Angiolipomas are painful subcutaneous nodules having all other features of a typical lipoma. [7]: 624 [9]
Erythema nodosum is a form of panniculitis characterised by tender red nodules, 1–10 cm, associated with systemic symptoms including fever, malaise, and joint pain. Nodules may become bluish-purple, yellowing, and green, and subside over a period of 2–6 weeks without ulcerating or scarring.
Pain or tenderness: The affected areas might be sore or painful to touch. Redness and swelling: The skin around the follicles can become red and swollen. Crusting and flaking: The scalp may ...
There are many factors to consider when diagnosing a malignant lump. Trouble swallowing or speaking, swollen cervical lymph nodes or a firm, immobile nodule are more indicative of malignancy, whereas a family history of autoimmune disease or goiter, thyroid hormonal dysfunction or a soft, painful nodule are more indicative of benignancy.