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  2. Thyroid-stimulating hormone - Wikipedia

    en.wikipedia.org/wiki/Thyroid-stimulating_hormone

    About 80% of this conversion is in the liver and other organs, and 20% in the thyroid itself. [1] TSH is secreted throughout life but particularly reaches high levels during the periods of rapid growth and development, as well as in response to stress. The hypothalamus, in the base of the brain, produces thyrotropin-releasing hormone (TRH).

  3. Hyperthyroidism - Wikipedia

    en.wikipedia.org/wiki/Hyperthyroidism

    The diagnosis of hyperthyroidism is confirmed by blood tests that show a decreased thyroid-stimulating hormone (TSH) level and elevated T 4 and T 3 levels. TSH is a hormone made by the pituitary gland in the brain that tells the thyroid gland how much hormone to make. When there is too much thyroid hormone, the TSH will be low.

  4. Common thyroid drug levothyroxine linked to bone mass loss - AOL

    www.aol.com/common-thyroid-drug-levothyroxine...

    People with high TSH and low T4 get a diagnosis of hypothyroidism. ... “Indications for prescribing levothyroxine include elevated TSH levels (indicating an underactive thyroid), fatigue, weight ...

  5. Thyroid disease - Wikipedia

    en.wikipedia.org/wiki/Thyroid_disease

    The most useful marker of thyroid gland function is serum thyroid-stimulating hormone (TSH) levels. TSH levels are determined by a classic negative feedback system in which high levels of T3 and T4 suppress the production of TSH, and low levels of T3 and T4 increase the production of TSH. TSH levels are thus often used by doctors as a screening ...

  6. Thyroid function tests - Wikipedia

    en.wikipedia.org/wiki/Thyroid_function_tests

    Thyroid hormone uptake (T uptake or T 3 uptake) is a measure of the unbound thyroxine binding globulins in the blood, that is, the TBG that is unsaturated with thyroid hormone. [2] Unsaturated TBG increases with decreased levels of thyroid hormones. It is not directly related to triiodothyronine, despite the name T 3 uptake. [2] Reference ranges:

  7. Euthyroid sick syndrome - Wikipedia

    en.wikipedia.org/wiki/Euthyroid_sick_syndrome

    Stress suppresses TSH, [5] and alterations in thyroid hormone levels may arise in psychiatric illness. In major depressive disorder, an NTIS-like phenotype may be observed, with reduced T3 and increased rT3. T4 may be elevated, and TSH is usually normal, although TSH's normal circadian rhythm may be disrupted. [2]

  8. Hypothalamic–pituitary–thyroid axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    The TSH, in turn, stimulates the thyroid to produce thyroid hormone until levels in the blood return to normal. Thyroid hormone exerts negative feedback control over the hypothalamus as well as anterior pituitary, thus controlling the release of both TRH from hypothalamus and TSH from anterior pituitary gland. [2]

  9. Thyrotoxic myopathy - Wikipedia

    en.wikipedia.org/wiki/Thyrotoxic_myopathy

    To understand how high levels of thyroxine can be toxic and lead to thyrotoxic myopathy physiologically, consider basic neuromuscular junction function. Under normal circumstances, muscle contraction occurs when electrical impulses travel down descending axons from the brain or spinal cord towards the neuromuscular junction .

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