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ILADS sustains the controversy as to the existence of "chronic Lyme disease", including advocating for long-term antibiotic treatment, but the existence of persistent borrelia infection is not supported by high quality clinical evidence, and the use of long term antibiotics is dangerous and contradicted. [4]
Chronic Lyme disease is distinct from untreated late-stage Lyme disease, which can cause arthritis, peripheral neuropathy and/or encephalomyelitis. Chronic Lyme disease is also distinct from post-treatment Lyme disease syndrome (PTLDS) when symptoms linger after standard antibiotic treatments.
The genomic variations have direct implications on the clinical symptoms of tick-borne Lyme disease. For example, B. burgdorferi s.s.’s tick-borne Lyme disease may manifest with arthritis-like symptoms. [9] In contrast, B. garinii’s tick-borne Lyme disease may cause an infection of the central nervous system. [9]
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"Erythema migrans is the only manifestation of Lyme disease in the United States that is sufficiently distinctive to allow clinical diagnosis in the absence of laboratory confirmation." [ 8 ] [ 9 ] Often, but not always, mentions of a target lesion (bull's-eye lesion) are talking about erythema migrans.
This is an accepted version of this page This is the latest accepted revision, reviewed on 3 August 2024. 2008 film about chronic Lyme disease Under Our Skin Theatrical poster Directed by Andy Abrahams Wilson Produced by Andrew Abrahams Distributed by Shadow Distribution Release dates April 2008 (2008-04) (Tribeca) June 19, 2009 (2009-06-19) (United States) Running time 103 minutes Country ...
Borrelia burgdorferi is a bacterial species of the spirochete class in the genus Borrelia, and is one of the causative agents of Lyme disease in humans. [1] [2] Along with a few similar genospecies, some of which also cause Lyme disease, it makes up the species complex of Borrelia burgdorferi sensu lato.
Acrodermatitis chronica atrophicans (ACA) is a skin rash indicative of the third or late stage of European Lyme borreliosis. ACA is a dermatological condition that takes a chronically progressive course and finally leads to a widespread atrophy of the skin. Involvement of the peripheral nervous system is often observed, specifically polyneuropathy.
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