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The diagnosis of bipolar disorder can be complicated by coexisting psychiatric conditions including obsessive–compulsive disorder, substance-use disorder, eating disorders, attention deficit hyperactivity disorder, social phobia, premenstrual syndrome (including premenstrual dysphoric disorder), or panic disorder.
[10] [11] A 2010 study found that "excellent performance" at school at age 15–16 was associated in males with a higher rate of developing bipolar disorder, but so was the poorest performance. [12] A 2005 study of young adult males found that poor performance on visuospatial tasks was associated with a higher rate of developing bipolar ...
Bipolar disorder is associated with elevated basal and dexamethasone elicited cortisol and adrenocorticotropic hormone (ACTH). These abnormalities are particularly prominent in mania, and are inversely associated with antipsychotic use. [97] The incidence of psychiatric symptoms associated with corticosteroids is between 6% and 32%.
Bipolar disorder – mental disorder with cyclical periods of depression and periods of elevated mood. [1] The elevated mood is significant and is known as mania , a severe elevation that can be accompanied by psychosis in some cases, or hypomania , a milder form of mania.
Low scores of 5 and below indicate a very low risk of a bipolar diagnosis. High scores of 18 and over indicate a high risk of a diagnosis of bipolar disorder, increasing the likelihood by a factor of seven or greater. [26] [5] Several peer-reviewed research studies support the P-GBI as a reliable and valid measure of bipolar in children and ...
A recent large-scale study found that severe depression in patients with bipolar disorder responds no better to a combination of antidepressant medications and mood stabilizers than it does to mood stabilizers alone and that antidepressant use does not hasten the emergence of manic symptoms in patients with bipolar disorder. [40]
An additional limitation is that the scale cannot confirm if an individual has bipolar disorder as it does not include all the signs of bipolar spectrum disorder listed by the DSM-5. A further limitation research studies are often conducted on small samples of outpatients, leading to varying scores of the accuracy and reliability of the BSDS. [2]
The Maudsley Bipolar Twin Study is an ongoing twin study of bipolar disorder running at the Institute of Psychiatry, King's College London since 2003. The study is investigating possible differences between people with a diagnosis of bipolar disorder and people without the diagnosis.