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The house mouse (Mus musculus) has a gestation period of 19 to 21 days. Key events in mouse brain development occur both before and after birth, beginning with peak neurogenesis of the cranial motor nuclei 9 days after conception, up to eye opening which occurs after birth and about 30 days after conception.
On November 14, 2008, the Allen Institute for Brain Science announced the launch of the Allen Developing Mouse Brain Atlas, providing a highly detailed map of gene activity in the mouse brain at several time points across development, [12] including four embryonic ages, three postnatal, and aging time points. [13]
The Allen Mouse Brain Atlas is a comprehensive genome-wide map of the adult mouse brain that reveals where each gene is expressed. [3] The mouse brain atlas was the original project of the Allen Brain Atlas and was finished in 2006. The purpose of the atlas is to aid in the development of neuroscience research.
Allen Brain Atlas [2] Mouse Brain Library [3] High resolution mouse brain atlas; BrainMaps. High-Resolution Brain Maps and Brain Atlases of Mus musculus; Despite superficial differences, especially in size and weight, the mouse brain and its function can serve as a powerful animal model for study of human brain diseases or mental disorders (see ...
A study reported that newly made cells in the adult mouse hippocampus can display passive membrane properties, action potentials and synaptic inputs similar to the ones found in mature dentate granule cells. These findings suggested that these newly made cells can mature into more practical and useful neurons in the adult mammalian brain. [33]
The development of sensory maps requires learning, long term potentiation, experience-dependent plasticity, and innate characteristics. [1] There is significant evidence for experience-dependent development and maintenance of sensory maps, and there is growing evidence on the molecular basis, synaptic basis and computational basis of experience ...
The interactive map required 1.4 petabytes of storage-space. [14] [15] About two months later, scientists reported that they created the first complete neuron-level-resolution 3D map of a monkey brain which they scanned via a new method within 100 hours. They made only a fraction of the 3D map publicly available as the entire map takes more ...
Genes involved in the neuro-development and in neuron physiology are extremely conserved between mammalian species (94% of genes expressed in common between humans and chimpanzees, 75% between humans and mice), compared to other organs. Therefore, few genes account for species differences in the human brain development and function. [15]