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Denosumab, sold under the brand name Prolia among others, is a human monoclonal antibody used for the treatment of osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone. [21] [22] The most common side effects are joint and muscle pain in the arms or legs. [23]
Prolia, approved in 2010 to treat bone loss in postmenopausal women and later approved to treat men and women at high risk of fracture, brought in total third-quarter sales of $986 million.
Butt rashes can occur due to a variety of causes, including psoriasis, hemorrhoids, and more. Here's what to know, plus how to treat and prevent butt rashes.
The symptoms of DRESS syndrome usually begin 2 to 6 weeks but uncommonly up to 8–16 weeks after exposure to an offending drug. Symptoms generally include fever, an often itchy rash which may be morbilliform or consist mainly of macules or plaques, facial edema (i.e. swelling, which is a hallmark of the disease), enlarged and sometimes painful lymph nodes, and other symptoms due to ...
Most often, a heat rash will take the form of small red bumps in splotches around your body. They can itch and be filled with fluid. Heat rashes usually appear suddenly within a few hours of ...
Gorham's disease (pronounced GOR-amz), also known as Gorham vanishing bone disease and phantom bone disease, [1] is a very rare skeletal condition of unknown cause.It is characterized by the uncontrolled proliferation of distended, thin-walled vascular or lymphatic channels within bone, which leads to resorption and replacement of bone with angiomas and/or fibrosis.
Bornholm disease, also known as epidemic pleurodynia, [1] is a condition characterized by myositis of the abdomen or chest caused by the Coxsackie B virus or other viruses. [2] The myositis manifests as an intermittent stabbing pain in the musculature that is seen primarily in children and young adults. [3]
Symptoms: Exposed bone after extraction, pain: Complications: Osteomyelitis of the jaw: Usual onset: After dental extractions: Duration: Variable: Types: Stage 1-Stage 3: Causes: Medications related to cancer therapy, and osteoporosis in combination with dental surgery: Risk factors: Duration of anti-resorptive or anti-angiogenic drugs ...