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  2. Anti–citrullinated protein antibody - Wikipedia

    en.wikipedia.org/wiki/Anti–citrullinated...

    Moreover, analysis of the correlation of anti-CCP antibody titre with RA disease activity yielded conflicting results. [13] [14] However, novel test systems utilizing ACPA have been developed. Citrullinated vimentin is a very promising autoantigen in RA, and a suitable tool for studying this systemic autoimmune disease. Vimentin is secreted and ...

  3. AE1/AE3 - Wikipedia

    en.wikipedia.org/wiki/AE1/AE3

    The antibody cocktail binds to cytokeratin 1 - 8, 10, 14 - 16 and 19 (but not CK17 or CK18). [1] It is therefore used as a marker of carcinomas, such as depth of invasion and metastases. [ 1 ] For example, it is both relatively sensitive and specific for detection of breast cancer metastasis to sentinel lymph nodes .

  4. Cytokeratin - Wikipedia

    en.wikipedia.org/wiki/Cytokeratin

    The term cytokeratin began to be used in the late 1970s, when the protein subunits of keratin intermediate filaments inside cells were first being identified and characterized. [2] In 2006 a new systematic nomenclature for mammalian keratins was created, and the proteins previously called cytokeratins are simply called keratins (human ...

  5. Keratin 14 - Wikipedia

    en.wikipedia.org/wiki/Keratin_14

    Keratin 14 was the first type I keratin sequence determined. [5] Keratin 14 is also known as cytokeratin-14 (CK-14) or keratin-14 (KRT14). In humans it is encoded by the KRT14 gene. [6] [7] [8] Keratin 14 is usually found as a heterodimer with type II keratin 5 and form the cytoskeleton of epithelial cells.

  6. Keratinocyte - Wikipedia

    en.wikipedia.org/wiki/Keratinocyte

    A Civatte body (named after the French dermatologist Achille Civatte, 1877–1956) [36] is a damaged basal keratinocyte that has undergone apoptosis, and consist largely of keratin intermediate filaments, and are almost invariably covered with immunoglobulins, mainly IgM. [37]

  7. Antibody elution - Wikipedia

    en.wikipedia.org/wiki/Antibody_elution

    An antibody elution removes bound antibody from the surface of a red blood cell to aid in the antibody identification process. An antibody elution is a clinical laboratory diagnostic procedure which removes sensitized antibodies from red blood cells , in order to determine the blood group system antigen the antibody targets. [ 1 ]

  8. 34βE12 - Wikipedia

    en.wikipedia.org/wiki/34βE12

    34βE12, often written as 34betaE12 and also known as CK34βE12 and keratin 903 (CK903), is an antibody specific for high molecular weight cytokeratins 1, 5, 10 and 14. [1] [2]It is sometimes, less precisely, referred to as high-molecular weight keratin (HMWK) and high-molecular weight cytokeratin (HMWCK).

  9. Mutated citrullinated vimentin - Wikipedia

    en.wikipedia.org/wiki/Mutated_citrullinated_Vimentin

    Anti-MCV antibodies are a member of the ACPA family, a group of the so-called antibodies to citrullinated protein/peptide antigens. Rheumatoid arthritis is an autoimmune disorder. Detection of specific autoantibodies (antibodies directed against the body’s own tissue) such as rheumatoid factors and ACPAs may provide indication of the disease.

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